Distribution of Rabbit Haemorrhagic Disease Virus RNA in Experimentally Infected Rabbits
Journal of Comparative Pathology, 2001Adult rabbits were inoculated with liver homogenate from a rabbit that died in a Japanese outbreak of rabbit haemorrhagic disease (RHD). All experimentally infected rabbits died with typical clinical, gross and histological findings of RHD. Distribution of RHD virus in tissues of the infected rabbits was studied by non-isotopic in-situ hybridization ...
T, Kimura +6 more
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Detection of rabbit haemorrhagic disease virus particles in the rabbit liver tissues
Journal of Comparative Pathology, 1992Liver tissues from rabbits experimentally infected with rabbit haemorrhagic disease virus (RHDV) were studied electron microscopically. The earliest change in hepatocytes of the rabbits infected with RHDV was hydropic degeneration. Rough endoplasmic reticulum was dilated with a mild increase in polysomes and cytoplasmic cisternae in degenerated ...
J H, Park, K, Ochiai, C, Itakura
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Recombination in Rabbit Haemorrhagic Disease Virus: Possible Impact on Evolution and Epidemiology
Rabbit haemorrhagic disease (RHD) was first recognised in 1984 following the introduction of apparently healthy rabbits into China from Germany. The aetiological agent Rabbit haemorrhagic disease virus (RHDV) has subsequently killed hundreds of millions ...
E A Gould, E A Gould, H Schirrmeier
exaly +2 more sources
A Competition ELISA for the Detection of Antibodies to Rabbit Haemorrhagic Disease Virus
Veterinary Microbiology, 1995Monoclonal antibodies (mAbs) were raised to a preparation of rabbit haemorrhagic disease virus (RHDV) purified from the livers of experimentally infected rabbits. Rabbit antisera to RHDV significantly blocked the binding of two mAbs (2D3(3) and 2D4(5)) to RHDV-coated microplate wells in a competition ELISA.
Victoria Boyd, H A Westbury
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Detection of a new variant of rabbit haemorrhagic disease virus in France
Veterinary Record, 2011WE wish to report the detection of a new variant of rabbit haemorrhagic disease virus (RHDV) (Lagovirus, Caliciviridae) which is circulating in France and has been causing high mortality in domestic and wild rabbit populations since the end of the summer of 2010. Rabbit haemorrhagic disease (RHD)
Le Gall-Reculé, Ghislaine +9 more
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Antigenicity of VP60 structural proteinof rabbit haemorrhagic disease virus
Archives of Virology, 1997Five overlapping segments of the VP60 capsid protein gene of rabbit haemorrhagic disease virus have been expressed in E. coli under the control of the T7 RNA polymerase. After purification, the antigenicity of these denatured protein segments has been studied by reactivity with sera from both naturally infected and vaccinated animals in Western blot ...
E, Viaplana, J, Plana, A, Villaverde
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Rabbit haemorrhagic disease virus type 2 in hares in England
Veterinary Record, 2019Rabbit haemorrhagic disease type 2 (RHDV2 or GI.21) is a highly infectious, usually fatal, disease of lagomorphs which has been present in the UK since 20102 and is now commonly diagnosed throughout the country.3 Similar to the rest of Europe, RHDV2 infection has been detected in European brown hares ( Lepus europaeus ) in England,4 although in a ...
Bell, Diana +6 more
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Detection of rabbit haemorrhagic disease virus antigen in tissues by immunohistochemistry
Research in Veterinary Science, 1992Formalin fixed liver, spleen, kidney, heart, lung, duodenum and appendix tissues from nine rabbits, experimentally infected with rabbit haemorrhagic disease virus (RHDV), were investigated for evidence of RHDV antigen by the direct avidin-biotin peroxidase complex immunohistochemical method.
J H, Park, C, Itakura
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Electron- and immunoelectron-microscopic investigation on the rabbit haemorrhagic disease virus
Comparative Immunology, Microbiology and Infectious Diseases, 1993Electron- and immunoelectron-microscopic methods were used for detection and investigation of rabbit haemorrhagic disease virus (RHDV). The observed virus particles were uncoated, with an icosahedral symmetry, with a 35-40 nm dia and capsids built up by 32 capsomers with a central hollow part and a 3.5-5 nm dia.
M, Alexandrov +4 more
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Hepatic lesions in young rabbits experimentally infected with rabbit haemorrhagic disease virus
Research in Veterinary Science, 1999Twenty young rabbits (eleven 2-week-old and nine 4-week-old) were experimentally infected with rabbit haemorrhagic disease virus (RHDV) to clarify susceptibility. They were killed chronologically up to 96 hours post-inoculation (PI) and examined for lesions.
O, Mikami +4 more
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