Results 121 to 130 of about 162,658 (282)

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

open access: yesBMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen   +7 more
wiley   +1 more source

Comparative Phylodynamics of Rabbit Hemorrhagic Disease Virus in Australia and New Zealand [PDF]

open access: yesJournal of Virology, 2015
ABSTRACTThe introduction of rabbit hemorrhagic disease virus (RHDV) into Australia and New Zealand during the 1990s as a means of controlling feral rabbits is an important case study in viral emergence. Both epidemics are exceptional in that the founder viruses share an origin and the timing of their release is known, providing a unique opportunity to ...
Janine A. Duckworth   +10 more
openaire   +3 more sources

Dicumarol [PDF]

open access: yes, 1945
Thesis (M.D.)--Boston ...
Steel, Robert MacDonald
core  

Immunosuppressive JAG2+ tumor‐associated neutrophils hamper PD‐1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells

open access: yesCancer Communications, EarlyView.
Abstract Background Tumor‐associated neutrophils (TANs) play a critical role in modulating immune responses and exhibit significant heterogeneity. Our previous study demonstrated that jagged canonical Notch ligand 2 (JAG2)+ TANs were associated with an immunosuppressive microenvironment in high‐grade serous ovarian cancer (HGSOC), but the underlying ...
Chenyang Wang   +11 more
wiley   +1 more source

Characteristics of a new variant of rabbit haemorrhagic disease virus – RHDV2

open access: yesActa Biologica, 2019
RHD (Rabbit Haemorrhagic Disease) is an etiologic agent that causes viral haemorrhagic disease of rabbits, which is also referred to as rabbit plague. The desire to explore knowledge about this pathogen in the world results not only from its similarity ...
Dominika Bębnowska   +1 more
doaj   +1 more source

Iodinated contrast media and cerebral hemorrhage after intravenous thrombolysis [PDF]

open access: yes, 2011
<p>Background and Purpose: Iodinated contrast is increasingly used in CT perfusion or angiographic examinations in acute stroke. Increased risk of intracranial hemorrhage (ICH) complicating microcatheter contrast injections has recently been ...
Evelyn Teasdale   +6 more
core   +1 more source

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves   +3 more
wiley   +1 more source

Wild rabbit management in the Iberian Peninsula: state of the art and future perspectives for Iberian lynx conservation [PDF]

open access: yes, 2017
The Iberian lynx, the most endangered cat in the world, is presently found only in two isolated populations in southern Spain. Natural expansion from these populations is limited which turns Iberian lynx reintroduction programs into the only alternative ...
Delibes-Mateos, Miguel   +1 more
core   +1 more source

Loss of the epithelial transcription factor grhl3 leads to variably penetrant developmental phenotypes in zebrafish

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Environmental influence is critical for embryogenesis but is significantly under‐appreciated under lab conditions, which are not typically designed to robustly test environmental variability. Here, we report environmental effects on the developmental phenotype of zebrafish lacking the transcription factor Grainyhead‐like 3 (grhl3 ...
Nishanthi Mathiyalagan   +5 more
wiley   +1 more source

Myeloperoxidase and Lysozymes as a Pivotal Hallmark of Immunity Status in Rabbits

open access: yesAnimals, 2020
Infectious diseases, due to their massive scale, are the greatest pain for all rabbit breeders. Viral infections cause enormous economic losses in farms. Treating sick rabbits is very difficult and expensive, so it is very important to prevent disease by
Rafał Hrynkiewicz   +2 more
doaj   +1 more source

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