Results 131 to 140 of about 20,605 (221)

Preeclampsia‐derived small extracellular vesicles disrupt blood–brain barrier integrity and activate glial cells in vitro

The Journal of Physiology, EarlyView.
Abstract figure legend This study assessed the impact of plasma‐derived small extracellular vesicles (sEVs) from healthy pregnant women and those diagnosed with late‐onset preeclampsia (PE) on the blood–brain barrier (BBB) integrity and glial cell response. PE patients had higher sEV concentrations than healthy controls.
Julián Henao‐Restrepo, José M. Murrieta‐Coxca, Christian Schmeer, Lingyu Wei, Frank Steiniger, Tanja Groten, Udo R. Markert, Diana M. Morales‐Prieto   +7 more
wiley   +1 more source

Inflammation induced by snake venoms optimizes envenomation

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustrating mechanisms underlying direct vascular absorption and subsequent movement of venom toxins into the tissues consequent to snakebite. A, snakebite into prey deposits venom toxins into the tissue interstitium, with the venom then causing acute inflammation primarily in venules.
Dirk F. van Helden, Neil Spratt, Peter J. Dosen, Sally A. McFadden, John Holdsworth, Daniel J Beard, Kirsten Coupland, Phillip Jobling, Todd A. Hardy, Derek R. Laver   +9 more
wiley   +1 more source

Photobiomodulation restores blood–brain barrier integrity after hypoxia via endothelial von Willebrand factor modulation in a humanised tricellular transwell model

The Journal of Physiology, EarlyView.
Abstract figure legend Photobiomodulation restores blood–brain barrier (BBB) integrity following hypoxic stress. A multicellular human BBB model comprising brain microvascular endothelial cells, astrocytes and pericytes was established in a transwell system and subjected to acute hypoxia.
Mirriam Domocos, Denis E. Bragin, Nagesh C. Shanbhag, Luise Schlotterose, Mootaz M. Salman   +4 more
wiley   +1 more source

An outbreak of rabbit hemorrhagic disease (RHD) caused by Lagovirus europaeus GI.2/rabbit hemorrhagic disease virus 2 (RHDV2) in Ehime, Japan. [PDF]

J Vet Med Sci, 2021
Katayama A, Miyazaki A, Okazaki N, Nakayama T, Mikami O.   +4 more
europepmc   +1 more source

Molecular characterization of rabbit hemorrhagic disease virus type 2 and long-lasting protection conferred by a VLP-based vaccine. [PDF]

BMC Vet Res
Wang Y, Qiao P, Wu H, Tong X, Wang T, Wang L, Yang Y, Su X, Liu C, Chen Y, Wang L, Wang M, Xi X, Wang F, Pang W, Liu Y, Tian K.   +16 more
europepmc   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Temporal Dynamics and Turnover of Rabbit Hemorrhagic Disease Virus 2 (RHDV2/GI.2) in Wild Lagomorphs from Northeastern Spain. [PDF]

Microb Ecol
Estruch J, Almeida T, Serrano E, Pereira L, Rouco C, Lavín S, Abrantes J, Velarde R, Lopes AM.   +8 more
europepmc   +1 more source

Utilizing blood filter paper and ear punch samples for the detection of rabbit hemorrhagic disease virus 2 by RT-rtPCR. [PDF]

J Vet Diagn Invest, 2022
Jennings-Gaines JE, Luukkonen KL, Robbins KM, Edwards WH, Vogt NA, Vogt AA, Allen SE.   +6 more
europepmc   +1 more source

Beyond Genes: Metabolomic Evidence Indicates Potential Species‐Level Differentiation in European Wild Rabbits

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 6, Page 645-656, July 2026.
ABSTRACT The European rabbit (Oryctolagus cuniculus) plays a key ecological role in Mediterranean ecosystems, yet its populations are declining. Two subspecies, O. c. algirus and O. c. cuniculus, are present in the Iberian Peninsula and exhibit genetic, phenotypic, and ecological differences.
César Cortés‐García, Mette Skou Hedemann, Jorge Mateo‐López, Lola Llobat, María Cambra‐López, Juan José Pascual, Ignacio García‐Bocanegra, Carlos Rouco, Pablo Jesús Marín‐García   +8 more
wiley   +1 more source

Protection Against Rabbit Hemorrhagic Disease Virus Strains: Efficacy of a New Commercial Recombinant RHDV2 Capsid Protein VP60 Vaccine. [PDF]

Vaccines (Basel)
Fontseca M, Perozo E, Nadal G, Gascón-Torrens S, Montané J, March R, Sitjà M.   +6 more
europepmc   +1 more source