Results 131 to 140 of about 36,243 (239)

Validation of Aortic Blood Flow Simulations During Extracorporeal Circulation Using Phase Contrast Magnetic Resonance Imaging

open access: yesArtificial Organs, EarlyView.
This is the first study assessing in vivo blood flow profiles during extracorporeal circulation (ECC) scenarios. Magnetic resonance imaging data served for the calibration of computational fluid dynamics algorithms, enabling accurate replication of the hemodynamic conditions.
Anna Kathrin Assmann   +9 more
wiley   +1 more source

Thrombospondin‐4 is upregulated in abdominal aortic aneurysm: A vasoprotective response with potential therapeutic relevance

open access: yesBritish Journal of Pharmacology, EarlyView.
TSP4 is upregulated in human and experimental AAA. TSP4 knockdown accelerated AAA formation and exacerbated both vascular inflammation and remodelling, emphasizing that TSP4 upregulation may represent a protective response against AAA. Our findings suggest that preserving TSP4 could be a useful strategy in the clinical management of AAA.
Laia Blanco‐Casoliva   +10 more
wiley   +1 more source

The role of fluvoxamine in the treatment of endotoxin‐induced acute heart injury

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Cardiovascular diseases are among the most common health problems worldwide. Inflammation plays a critical role in the pathogenesis of various heart diseases. Lipopolysaccharides (LPS) trigger inflammatory mechanisms, leading to an inflammatory response.
Ilter Ilhan   +5 more
wiley   +1 more source

Rabbit hemorrhagic disease (RHD): characterization of the causative calicivirus.

open access: yesVeterinary research, 1993
Rabbit hemorrhagic disease (RHD) which was first recognized in China in 1984 spread via Eastern Europe to many countries of Western Europe and other parts of the world. The analysis of the virus outlined in this review comprises: 1) physico-chemical properties, 2) electron microscopy including immunoelectron microscopy, 3) demonstration of capsid ...
Ohlinger, Vf, Haas, B, Thiel, Hj
openaire   +2 more sources

Use of a 3D‐printed custom‐designed tracheostomy tube to stabilise a permanent tracheostoma in a 25‐year‐old Icelandic mare

open access: yesEquine Veterinary Education, EarlyView.
Summary A 25‐year‐old Icelandic mare diagnosed with bilateral temporohyoid‐osteoarthropathy, moderate pharyngeal instability and bilateral laryngeal paralysis was presented because of intermittent stridor and dyspnoea worsening during exercise. As a previous ceratohyoidectomy had not improved these symptoms substantially, a permanent tracheostomy was ...
D. C. Debald   +3 more
wiley   +1 more source

Air embolism secondary to suspected lymphatic tissue disruption with severe exercise‐induced pulmonary haemorrhage

open access: yesEquine Veterinary Education, EarlyView.
Summary Air embolism is rare in horses and typically associated with complications following intravenous catheterisation or other medical procedures. Exercise‐induced pulmonary haemorrhage (EIPH) is common in racehorses but not usually associated with air embolism. This report describes a case of air embolism in a 4‐year‐old Thoroughbred with EIPH. The
J. Wittenberg   +7 more
wiley   +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

open access: yesThe FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin   +2 more
wiley   +1 more source

ALOX15 mediates thrombin‐induced myristoylation, trafficking, and interaction of protease‐activated receptors, leading to platelet activation and hemostasis

open access: yesThe FEBS Journal, EarlyView.
The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati   +4 more
wiley   +1 more source

Establishment of an MRI‐Based Diagnostic Approach to Identify Critical Pulpal Inflammation Zones in a Rat Caries‐Derived Pulpitis Model

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Aim To establish a magnetic resonance imaging (MRI)‐based diagnostic approach for identifying ‘critical pulpal inflammation’ zones in a rat model of caries‐derived pulpitis. Methodology Caries‐derived pulpitis was induced in the molars of Sprague–Dawley rats using the caries‐derived pulpitis model.
Kiichi Moriyama   +7 more
wiley   +1 more source

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