Results 141 to 150 of about 161,155 (272)

Involvement of Piezo 1 in inhibition of shear‐induced platelet activation and arterial thrombosis by ginsenoside Rb1

British Journal of Pharmacology, Volume 182, Issue 9, Page 1957-1974, May 2025.
Abstract Background and Purpose Shear‐induced platelet activation and aggregation (SIPA) play crucial roles in arterial thrombosis. Piezo1 is a mechanosensitive calcium channel that promotes platelet hyperactivation under pathological high‐shear conditions.
Yilin Wang, Lu Liu, Jia Li, Yue You, Shunli Xiao, Jiantao Feng, Xiaojie Yin, Fulong Liao, Yun You   +8 more
wiley   +1 more source

Tracking the Origin of a Rabbit Haemorrhagic Virus 2 Outbreak in a Wild Rabbit Breeding Centre in Portugal; Epidemiological and Genetic Investigation [PDF]

, 2016
As key prey, the wild rabbit downsize constitutes a major drawback on the endangered Iberian lynx (Lynx pardinus) re-introduction in the Iberia. Several captive breeding units mostly located in Alentejo, endeavour the wild rabbit repopulation of depleted
Barros, Sílvia, Branco, Sandra, Carvalho, CL, Duarte, Elsa Leclerc, Duarte, Margarida Dias, Fagulha, Teresa, Fevereiro, Miguel, Henriques, Ana Margarida, Melo, Pedro, Monteiro, Madalena, Ramos, Fernanda, Rodeia, Joana, Tavares Santos, Patricia   +12 more
core   +1 more source

Feasibility of Intratumoral Administration With EPHB4‐CAR‐T Cells for the Treatment of Oral Squamous Cell Carcinoma

Cancer Science, Volume 116, Issue 5, Page 1227-1238, May 2025.
Oral squamous cell carcinoma (OSCC), the most common type of oral cancer, has a poor prognosis. This study found high Ephrin type‐B receptor 4 (EPHB4) expression, mainly localized on the tumor cell membrane, in most OSCC cases, suggesting EPHB4 as a promising target for chimeric antigen receptor (CAR) T cell therapy.
Yusuke Ito, Toshihiro Suzuki, Manami Shimomura, Kazumasa Takenouchi, Kazunobu Ohnuki, Kayoko Shoda, Yuka Kenmochi, Shigeki Yagyu, Kazuto Matsuura, Ryuichi Hayashi, Tetsuya Nakatsura   +10 more
wiley   +1 more source

Stroke‐Homing Peptide‐DNase1 Alleviates Intestinal Ischemia Reperfusion Injury by Selectively Degrading Neutrophil Extracellular Traps

Cell Proliferation, EarlyView.
SHp‐DNase1 combined with CRO inhibits NETs to alleviate intestinal IRI ABSTRACT Neutrophil extracellular traps (NETs) act as a vital first line of defence against tissue damage and pathogens, playing a significant role in improving diseases such as intestinal ischemia reperfusion injury (IRI).
Tingting Liu, Xinrong Lv, Qingshan Xu, Xiuting Qi, Shenghui Qiu, Yaqi Luan, Na Shen, Jing Cheng, Lan Jin, Tian Tian, Wentao Liu, Lai Jin, Zhongzhi Jia   +12 more
wiley   +1 more source

KYNA Ameliorates Hepatic Ischemia–Reperfusion Injury by Activating the Hippo Signalling Pathway via FTO‐Dependent m6A Demethylation of LATS1

Cell Proliferation, EarlyView.
Our study elucidates the cellular and molecular mechanisms underlying KYNA's protective effects against HIRI. It emphasises that KYNA modulates the methylation status of the Hippo signalling pathway through the activation of AHR, thereby mitigating damage by promoting LATS1 degradation and facilitating the nuclear translocation of YAP. ABSTRACT Hepatic
Wenjie Zheng, Xiaowen Wang, Haoqi Chen, Kaiming He, Xijing Yan, Yuan Zhang, Yang Yang, Peng Zhang, Wenfeng Zhu, Shuguang Zhu, Hua Li   +10 more
wiley   +1 more source

Torque teno virus as a marker of immune status in immunocompromised patients: A systematic review

European Journal of Clinical Investigation, EarlyView.
Abstract Background Torque teno virus (TTV) is not known to cause disease in humans; however, chronic inflammatory conditions and immunosuppression states can favour TTV replication. This study aimed to verify the effectiveness of TTV as an immune biomarker.
Janaina B. Medina, Fábio França Vieira e Silva, Rafael Antônio Velôso Caixeta, Bruna de Oliveira Rech, Alba Perez‐Jardón, María Elena Padín‐Iruegas, Mario Pérez‐Sayáns, Paulo Henrique Braz‐Silva, Karem L. Ortega   +8 more
wiley   +1 more source

Evaluation of a prepared combined inactivated vaccine against hemorrhagic disease virus 2 and Clostridium perfringens type A infections in rabbit

VacciMonitor
Rabbit hemorrhagic disease virus 2 and Clostridium perfringens type A cause infections in rabbit. Vaccines are considered an effective strategy for fighting these infections.
Mahmoud M. Abotaleb, Rasha G. Tawfik, Dalia M. Omar, Farida H. Mohamed, Shereen M. Aly, Noura M. Khalaf, Samir A. Nassif   +6 more
doaj  

Two decades of occurrence of non-pathogenic rabbit lagoviruses in Italy and their genomic characterization

Scientific Reports
Lagoviruses are viruses of the Caliciviridae family affecting lagomorphs. Both pathogenic and non-pathogenic lagoviruses affect the European rabbit (Oryctolagus cuniculus), and they are phylogenetically distinguished.
Patrizia Cavadini, Alice Vismarra, Francesca Merzoni, Vittoria Di Giovanni, Maria Beatrice Boniotti, Lorenzo Capucci, Antonio Lavazza   +6 more
doaj   +1 more source

Return of a racehorse to racing after iatrogenic lipoid pneumonia

Equine Veterinary Education, EarlyView.
Summary There is a paucity of literature describing equine lipoid pneumonia (LP) caused by inadvertent intrapulmonary administration of liquid paraffin (mineral oil). This case report improves our understanding of LP by describing; (1) the first reported return of a horse to racing after LP, (2) the likely benefits of prolonged dexamethasone ...
S. McCullagh, M. C. M. Dosi, J. A. Keen, N. Parkinson, A. Tay, B. C. McGorum   +5 more
wiley   +1 more source

België ontsnapt niet aan het 'rabbit hemorrhagic disease virus-2' [PDF]

, 2016
Since 2016, an extensive spread of RHDV2, a virus variant of the classical rabbit hemorrhagic disease virus (RHDV) is ongoing in the Belgian rabbit population. Both variants of the virus usually cause acute death without prior symptoms.
Hermans, Katleen, Moeremans, Ilse, Verlinden, Marc, Garmyn, An   +3 more
core   +1 more source