Results 211 to 220 of about 5,012,000 (246)

A Role for Glycine Transporter‐2 Inhibitors in Regulating Accumbal Dopamine Levels and Voluntary Alcohol Intake in Rats

Alcohol, Clinical and Experimental Research, Volume 50, Issue 9, September 2026.
Partial inhibition of glycine transporter‐2 (GlyT2) elevates basal dopamine levels in the nucleus accumbens and abolishes the alcohol deprivation effect in rats. The findings reveal a role for GlyT2‐expressing glycinergic neurons in regulating mesolimbic dopamine signaling and relapse‐like alcohol drinking, highlighting GlyT2 as a potential target for ...
Yasmin Olsson, Klara Danielsson, Ana Domi, Helga Lidö, Linda Engström Ruud, Mia Ericson, Bo Söderpalm   +6 more
wiley   +1 more source

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An Outbreak of Rabbit Hemorrhagic Disease in Finland

Journal of Wildlife Diseases, 2018
Rabbit hemorrhagic disease (RHD) was detected in European rabbits ( Oryctolagus cuniculus) for the first time ever in Finland in 2016. Reports of dead feral rabbits in Helsinki started to accumulate from April 2016. The Finnish Food Safety Authority Evira received the first animals in late April, and the main necropsy finding was severe, acute ...
Aleksija Neimanis, Tiina Nokireki, Riikka Holopainen   +2 more
exaly   +3 more sources

Early Pathogenesis in Rabbit Hemorrhagic Disease Virus 2

SSRN Electronic Journal, 2022
To detail early tissue distribution and innate immune response to rabbit hemorrhagic disease virus 2 (RHDV2), 13 rabbits were orally (Oryctolagus cuniculus) inoculated with liver homogenate made from a feral rabbit that succumbed to RHDV2 during the 2020 outbreak in Oregon, USA.
Alicia D. O'Toole, Fawzi M. Mohamed, Jian Zhang, Corrie C. Brown   +3 more
openaire   +2 more sources

An Outbreak of Rabbit Hemorrhagic Disease in British Columbia, Canada

Journal of Wildlife Diseases, 2021
From 2018 to 2019, an outbreak of rabbit hemorrhagic disease virus 2 occurred in British Columbia, Canada, in feral and domestic European rabbits (Oryctolagus cuniculus). Anthropogenic translocation of infected animals is suspected to have played a role in the introduction and spread of the virus.
Chelsea G, Himsworth, Doris, Leung, Kaylee, Byers, Tomy, Joseph, Emilia, Gordon, Helen, Schwantje, Jane, Pritchard, Aruna, Ambagala   +7 more
openaire   +2 more sources

Outbreak of rabbit hemorrhagic disease in domestic lagomorphs

Journal of the American Veterinary Medical Association, 2003
Abstract
Enzo R, Campagnolo, Mark J, Ernst, Mary L, Berninger, Douglas A, Gregg, Thomas J, Shumaker, Aida M, Boghossian   +5 more
openaire   +2 more sources

Down the Rabbit Hole: Domestic Rabbit Owners’ Perceptions of Rabbit Hemorrhagic Disease Virus 2

EcoHealth, 2022
Rabbit hemorrhagic disease virus 2 (RHDV2) is a highly contagious pathogen that infects wild and domestic rabbits and hares (lagomorphs). Globally, RHDV2 has resulted in substantial economic losses for commercial rabbit trade and caused wild lagomorph population declines.
Hannah G. Shapiro, Mark G. Ruder, Elizabeth F. Pienaar   +2 more
openaire   +3 more sources

Adenovirus-based oral vaccine for rabbit hemorrhagic disease

Veterinary Immunology and Immunopathology, 2012
Vaccine antigens for rabbit hemorrhagic disease virus (RHDV) are currently derived from inactivated RHDV obtained from the livers of experimentally infected rabbits or from several recombinant immunogens. However, the application of these vaccine antigens has been restricted because of biosecurity and immunity characteristics.
Xinglong, Wang, Li, Qiu, Huafang, Hao, Weidong, Zhang, Xiangjing, Fu, Hongling, Zhang, Shengfang, He, Shuxia, Zhang, Enqi, Du, Zengqi, Yang   +9 more
openaire   +2 more sources

[The hemorrhagic disease of rabbits. "Rabbit hemorrhagic disease" (RHD)].

DTW. Deutsche tierarztliche Wochenschrift, 1993
The rabbit hemorrhagic disease which was first described in 1984 caused high losses in rabbit holdings of many countries. The disease and its causative agent are reviewed with regard to clinical symptoms, pathology, etiology, molecular biology, diagnosis, epidemiology and control.
B, Haas, H J, Thiel
openaire   +1 more source

Programmed cell death in the pathogenesis of rabbit hemorrhagic disease

Archives of Virology, 1998
Rabbit hemorrhagic disease is a rapidly lethal infection caused by a calicivirus, characterized by acute liver damage and disseminated intravascular coagulation (DIC). Following morphological criteria and using a specific in situ labeling technique, we have found that liver cell death induced upon infection is due to apoptosis, and that programmed cell
Alonso Martí, Covadonga, Oviedo, J. M., Martín-Alonso, José Manuel, Díaz, Eduardo, Boga, José Antonio, Parra, Francisco   +5 more
openaire   +3 more sources

Structural Basis for Rabbit Hemorrhagic Disease Virus Antibody Specificity

Journal of Virology, 2022
Isolated RHDV antibodies have been used for decades to distinguish between antigenic variants, monitor temporal capsid evolution, and examine neutralizing capacities. In this study, we provided the structural basis for an RHDV GI.2 specific diagnostic antibody (2D9) binding and reveal that a small number of amino acid substitutions at the binding site ...
Mila M. Leuthold, Turgay Kilic, Jessica M. Devant, Oscar Landeta, Francisco Parra, Kevin P. Dalton, Grant S. Hansman   +6 more
openaire   +2 more sources