Results 81 to 90 of about 24,834 (201)

Detection and preliminary characterization of a new rabbit calicivirus related to rabbit hemorrhagic disease virus but nonpathogenic [PDF]

Journal of Virology, 1996
A new rabbit calicivirus related to the rabbit hemorrhagic disease virus (RHDV) was identified. The new virus contains significant differences from the previously characterized RHDV isolates in terms of pathogenicity, viral titer, tropism, and primary sequence of the structural protein.
M L Pacciarini, P Fusi, C Rossi, Antonio Lavazza, Lorenzo Capucci   +4 more
openaire   +3 more sources

Immunological Cross-Protection between Different Rabbit Hemorrhagic Disease Viruses—Implications for Rabbit Biocontrol and Vaccine Development

Vaccines, 2022
The use of rabbit hemorrhagic disease virus (RHDV) as a biocontrol agent to control feral rabbit populations in Australia, in combination with circulating endemic strains, provides a unique environment to observe the interactions between different ...
Tiffany W. O’Connor, Andrew J. Read, Robyn N. Hall, Tanja Strive, Peter D. Kirkland   +4 more
doaj   +1 more source

Engineering DNA Origami Captors for TGFβ1 Sequestration to Enhance Tumor Immune Modulation and Therapy

Advanced Science, EarlyView.
Programmable DNA framework captors effectively deplete circulatingtransforming growth factor‐β1 (TGFβ1) through fast systemic clearance and reshape the tumor immune microenvironment, alleviating immunosuppression to inhibit tumor progression. Abstract Efficient modulation of pivotal immune‐regulatory molecules to leverage the tumor microenvironment ...
Xiao Chen, Dunfang Liu, Jiahui Jin, Han Yao, Yao Sheng, Yarong Liu, Jingwei Sun, Yang Yang   +7 more
wiley   +1 more source

Characteristics of a new variant of rabbit haemorrhagic disease virus – RHDV2

Acta Biologica, 2019
RHD (Rabbit Haemorrhagic Disease) is an etiologic agent that causes viral haemorrhagic disease of rabbits, which is also referred to as rabbit plague. The desire to explore knowledge about this pathogen in the world results not only from its similarity ...
Dominika Bębnowska, Paulina Niedźwiedzka-Rystwej   +1 more
doaj   +1 more source

Dynamics of Humoral Immunity to Myxoma and Rabbit Hemorrhagic Disease Viruses in Wild European Rabbits Assessed by Longitudinal Semiquantitative Serology

Microbiology Spectrum, 2023
Myxoma virus (MYXV) and rabbit hemorrhagic disease virus (RHDV) are important drivers of the population decline of the European rabbit, an endangered keystone species.
Joana Coelho, Henrique Pacheco, Marta Rafael, Saúl Jiménez-Ruiz, Paulo Célio Alves, Nuno Santos   +5 more
doaj   +1 more source

Immunogenicity and Efficacy of a Bivalent Inactivated Vaccine against Rabbit Hemorrhagic Disease Virus

World's Veterinary Journal, 2022
Rabbit hemorrhagic disease is a fatal threat to rabbits that causes sustainability problems and substantial economic losses. The aim of the current study was to compare the immuno-enhancing effects of a bivalent inactivated rabbit hemorrhagic disease ...
S. Abodalal, M. A. Abdrabo, L. Omar
semanticscholar   +1 more source

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

Advanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song, Xiaokai Zhang, Zihang Huang, Zhiqiang Pei, Linqi Zeng, Fengze Cai, Tongyao Wang, Mohan Li, Chenyan Liu, Yining Song, Jiahao Guo, Hao Lu, Xinyu Weng, Li Shen, Xiaochun Zhang, Xingxing Cai, Aijun Sun, Junbo Ge   +17 more
wiley   +1 more source

Transplanting neural stem cells overexpressing miRNA‐21 can promote neural recovery after cerebral hemorrhage through the SOX2/LIN28‐let‐7 signaling pathway

Animal Models and Experimental Medicine, EarlyView.
Abstract Background Intracerebral hemorrhage (ICH) remains a devastating neurological disorder with limited therapeutic options. Neural stem cell (NSC)‐based therapies have emerged as a potential regenerative approach, yet the molecular mechanisms regulating NSC behavior require further elucidation.
Wei Dai, Yongxia Li, Jiarui Du, Gang Shen, Meimei Fan, Zuopeng Su, Fulin Xu, Fang Yuan   +7 more
wiley   +1 more source

Negative trends in Rabbit populations in ‘Pest’ and ‘Non-Pest’ areas of central Spain after the outbreak of rabbit hemorrhagic disease virus 2

Zeitschrift f\ ur Jagdwissenschaft
Despite increased conservation efforts, the European rabbit (Oryctolagus cuniculus), a keystone species in the Iberian Peninsula, continues declining due to habitat degradation and viral diseases. Following the 2011 outbreak of Rabbit Hemorrhagic Disease
Cristina Marin-Sáez, M. Delibes‐Mateos, Brian Cooke, Simone Santoro, F. Castro, R. Villafuerte   +5 more
semanticscholar   +1 more source

Comparative susceptibility of eastern cottontails and New Zealand white rabbits to classical rabbit hemorrhagic disease virus (RHDV) and RHDV2.

Transboundary and Emerging Diseases, 2021
Rabbit hemorrhagic disease virus (RHDV) is associated with high morbidity and mortality in the European rabbit (Oryctolagus cuniculus). In 2010, a genetically distinct RHDV named RHDV2 emerged in Europe and spread to many other regions, including North ...
F. Mohamed, T. Gidlewski, M. Berninger, H. Petrowski, A. Bracht, Carla Bravo de Rueda, R. Barrette, M. Grady, E. O’Hearn, C. Lewis, K. Moran, Tracy L. Sturgill, L. Capucci, J. Root   +13 more
semanticscholar   +1 more source