RNAi Inhibition of Rabbit Hemorrhagic Disease Virus (RHDV) Gene Expression in CHO Cell Line [PDF]
مجلة جامعة النجاح للأبحاث العلوم الطبيعية, 2008 Rabbit hemorrhagic disease virus (RHDV) causes great losses and is life threatening to both wild and domestic rabbits. This work represents the first step toward production of transgenic rabbits resistant to RHDV by RNAi through the inhibition of ...
Bilal Ghareeb
doaj +5 more sources
Development of a SYBR-based real-time PCR to detect rabbit hemorrhagic disease virus (RHDV) and analyze its tissue distribution in experimentally infected rabbits. [PDF]
Virol Sin, 2015 In this study, we developed a real-time PCR assay for RHDV detection and quantitation. With this method, the distribution of RHDV in the internal organs and body fluids of infected rabbits was analyzed. The highest viral RNA load was found in the spleen, followed by that in the liver.
Liu W, Dang R, Wang X.
europepmc +8 more sources
Taiwan Veterinary JournalThe renal cells were isolated from the kidney of different week-age of healthy rabbits by a single two-stage pass perfusion method and suspended in Hanks’ balanced salt solution (Ca[Formula: see text]-, Mg[Formula: see text]-free).
Hyok Ryo +3 more
semanticscholar +3 more sources
Agricultural Science and PracticeAim. This study aimed to develop a specific and sensitive multiplex real-time reverse transcription PCR (RT-qPCR) method for the detection and differentiation of rabbit hemorrhagic disease virus (RHDV) genotypes GI.1 and GI.2 circulating in Ukraine ...
A.A. Mezhenskyi +4 more
semanticscholar +4 more sources
Epitope mapping of a neutralizing antibody against rabbit hemorrhagic disease virus GI.2 [PDF]
Veterinary ResearchIn 2010, rabbit hemorrhagic disease virus (RHDV) GI.2 emerged, and unlike RHDV GI.1, it caused mortality in young rabbits, while existing vaccines were not fully protective.
Ana Podadera +7 more
doaj +3 more sources
Detection of a New Recombinant Rabbit Hemorrhagic Disease Virus 2 in China and Development of Virus-like Particle-Based Vaccine [PDF]
VirusesRabbit hemorrhagic disease virus (RHDV) is a very virulent virus of the genus Lagovirus causing severe and fatal hepatitis in the European rabbit (Oryctolagus cuniculus). RHDV has two distinct genotypes: GI.1 (RHDV) and GI.2 (RHDV2). The first RHDV2/GI.2
Bo Hu +5 more
doaj +3 more sources
Rabbit Hemorrhagic Disease Virus 2 (RHDV2; GI.2) Is Replacing Endemic Strains of RHDV in the Australian Landscape within 18 Months of Its Arrival [PDF]
Journal of Virology, 2017 ABSTRACT Rabbit hemorrhagic disease virus 2 (RHDV2; Lagovirus GI.2) is a pathogenic calicivirus that affects European rabbits ( Oryctolagus cuniculus ) and various hare ( Lepus ) species.
Jackie E. Mahar +13 more
semanticscholar +5 more sources
Virus Research, 1992 Purified preparations of the Spanish field isolate of rabbit hemorrhagic disease virus AST/89 were found to contain the plus-stranded genomic RNA of more than 7.4 kilobases (kb) and large amounts of a subgenomic mRNA of 2.4 kb. The smaller RNA was translated in vitro and shown to code for a 60 kDa protein which was immunoprecipitated using anti-RHDV as
José Antonio Boga +4 more
semanticscholar +5 more sources
Novel Calicivirus Identified in Rabbits, Michigan, USA [PDF]
Emerging Infectious Diseases, 2009 We report a disease outbreak in a Michigan rabbitry of a rabbit calicivirus distinct from the foreign animal disease agent, rabbit hemorrhagic disease virus (RHDV). The novel virus has been designated Michigan rabbit calicivirus (MRCV).
Ingrid L. Bergin +5 more
doaj +3 more sources
Erratum to: Identification of two novel rabbit hemorrhagic disease virus (RHDV) B cell epitopes and evaluation of its immunoprotection against RHDV [PDF]
Applied Microbiology and Biotechnology, 2015 Desheng Kong +9 more
semanticscholar +3 more sources