Inhibition of interferon signaling improves rabbit calicivirus replication in biliary organoid cultures [PDF]
The Rabbit hemorrhagic disease virus (RHDV) was discovered 40 years ago. This highly pathogenic virus threatens the integrity of ecosystems in the European rabbit’s native range, while in Australia, it is used as a biocontrol tool to manage overabundant ...
Elena Smertina +7 more
doaj +2 more sources
The Baculovirus Expression System Expresses Chimeric RHDV VLPs as Bivalent Vaccine Candidates for Classic RHDV (GI.1) and RHDV2 (GI.2) [PDF]
Background: Rabbit hemorrhagic disease (RHD) is an acute, hemorrhagic and highly lethal infectious disease caused by rabbit hemorrhagic disease virus (RHDV), which causes huge economic losses to the rabbit breeding industry.
Yan Wang +6 more
doaj +2 more sources
To mitigate the negative impacts of invasive rabbits in Australia, land managers are permitted to release the biocontrol virus, rabbit hemorrhagic disease virus (RHDV), to reduce rabbit numbers.
Patrick L. Taggart +7 more
doaj +2 more sources
Histo-blood group antigens act as attachment factors of rabbit hemorrhagic disease virus infection in a virus strain-dependent manner. [PDF]
Rabbit Hemorrhagic disease virus (RHDV), a calicivirus of the Lagovirus genus, and responsible for rabbit hemorrhagic disease (RHD), kills rabbits between 48 to 72 hours post infection with mortality rates as high as 50-90%.
Kristina Nyström +12 more
doaj +5 more sources
A pandemic strain of calicivirus threatens rabbit industries in the Americas [PDF]
Rabbit Hemorrhagic Disease (RHD) is a severe acute viral disease specifically affecting the European rabbit Oryctolagus cuniculus. As the European rabbit is the predominant species of domestic rabbit throughout the world, RHD contributes towards ...
Botti Giuliana +10 more
doaj +6 more sources
Simultaneous Occurrence of Field Epidemics of Rabbit Hemorrhagic Disease (RHD) in Poland Due to the Co-Presence of <i>Lagovirus europaeus</i> GI.1 (RHDV)/GI.1a (RHDVa) and GI.2 (RHDV2) Genotypes. [PDF]
The highly fatal rabbit hemorrhagic disease (RHD) that first emerged in 1984 in China has spread worldwide and affects both domestic and wild rabbits. The disease was originally caused by RHD virus (Lagovirus europaeus, L.europaeus) of GI.1 genotype, but
Fitzner A +2 more
europepmc +2 more sources
Two decades of occurrence of non-pathogenic rabbit lagoviruses in Italy and their genomic characterization [PDF]
Lagoviruses are viruses of the Caliciviridae family affecting lagomorphs. Both pathogenic and non-pathogenic lagoviruses affect the European rabbit (Oryctolagus cuniculus), and they are phylogenetically distinguished.
Patrizia Cavadini +6 more
doaj +2 more sources
Neglected Spleen Transcriptional Profile Reveals Inflammatory Disorder Conferred by Rabbit Hemorrhagic Disease Virus 2 Infection [PDF]
Rabbit hemorrhagic disease (RHD) is an acute fatal disease caused by the rabbit hemorrhagic disease virus (RHDV). Since the first outbreaks of type 2 RHDV (RHDV2) in April 2020 in China, the persistence of this virus in the rabbit population has caused ...
Jifeng Yu +19 more
doaj +2 more sources
Screening optimal DC-targeting peptide to enhance the immune efficacy of recombinant Lactobacillus expressing RHDV VP60 [PDF]
Dendritic cells (DCs) present an ideal target for delivering immunogenic cargo due to their potent antigen-presenting capabilities. This targeting approach holds promise in vaccine development by enhancing the efficiency of antigen recognition and ...
Tian Xia +15 more
doaj +2 more sources
Domestic European Rabbits <i>Oryctolagus cuniculus</i>: A Super-Highway for the Spread of Emergent Viral Diseases to Other Lagomorphs? [PDF]
We propose that the worldwide spread of several viral diseases in European rabbits (Oryctolagus cuniculus) is facilitated by domestic rabbit meat production and associated international trade. This view is based on published records of the transfer of rabbit haemorrhagic disease viruses (RHDV/RHDV2) between countries and supported by data from the Food
Angulo E +3 more
europepmc +2 more sources

