Results 91 to 100 of about 1,426,128 (326)

Changes of Hematological and Hemorheological Parameters in Rabbits with Hypercholesterolemia [PDF]

, 2021
Bence Tánczos, Viktória Somogyi, Mariann Bombicz, Béla Juhász, Norbert Németh, Ádám Deák   +5 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Studies on the compounds lipids from X-ray irradiated animal,1. [PDF]

, 1962
For the purpose to reveal the mechanism of the biological indirect action of X-rays the author has conducted the analysis of the compound lipids of the organs of the rabbits irradiated with X-rays.
Ohara, Sachiko
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Effects of different time schedules for regrouping on socio-positive behaviors in group-housed rabbit does [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi
Many studies have demonstrated that group housing of does often results in aggression and sometimes lesions due to biting. However, the positive interactions among reproducing does in group housing systems is less clear.
Metin PETEK, Sabine G. GEBHARDT-HENRICH
doaj   +1 more source

Consistency of Skinner Box Activity Measures in the domestic Rabbit (Oryctolagus cuniculus) [PDF]

, 1997
Consistency of individual differences in several measures of Skinner box operant and other activity and their intercorrelations in 14 chinchilla bred rabbits were studied.
Budaev, Dr. Sergey V., Zworykin, Dr. Dmitry D., Zworykina, Dr. Svetlana V.   +2 more
core   +1 more source

Mechanism of Action of Acupotomy in Inhibiting Chondrocyte Apoptosis in Rabbits with KOA through the PI3K/Akt Signaling Pathway [PDF]

, 2020
Xiao-shuang Huang, Kai Geng, Shiyu Luo, Cun-bin Liu, Kai-ning Yang, Ao Zhai, Yonghui Yang   +6 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Modelling for research on chemical control of mammals in New Zealand [PDF]

, 1974
Development of predictive formulae or qualitative statements about the probable outcome of control campaigns entails knowledge of bait quality and distribution, behaviour, vagaries of weather at the time of the control campaign, and other factors which ...
Batcheler, C. L., Bell, J.
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source