Results 91 to 100 of about 1,533,449 (332)
Molecular Oncology, EarlyView.We investigated whether hypomethylating agents (HMAs) used in myeloid malignancies induce somatic retrotransposition. Our findings indicate that HMA treatment increases L1‐encoded protein expression but does not lead to detectable de novo retrotransposition events in either patient samples or cell lines.
Šárka Pavlová +14 more
wiley +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
THE ACTION OF SULPHANILAMIDE ON RABBITS' LENSES IN VITRO [PDF]
, 1947 A. Bakker
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Application of rabbits in biomedical research: A review
, 2010 The first transgenic rabbits were obtained two decades ago by pronuclear microinjection. Several characteristics of rabbit made it the first and classical model for the study of lipoproteins and atherosclerosis.
Z. Bősze, L. Houdebine
semanticscholar +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Does "rabbit" refer to rabbits?
European Journal of Analytic Philosophy, 2005 It is commonly presupposed that all instances of the deflationary reference schema ‘F’ applies to x if and only if x is ‘are correct. This paper argues, mainly on the basis of concrete example, that we have little reason to be confident about this presupposition: our tendency to believe the instances is based on local successes that may not be globally
openaire +2 more sources
Metabolism of some ω-halogenoalkylbenzenes and related alcohols in the rabbit [PDF]
, 1958 H. G. Bray, Sybil P. James, W. V. Thorpe
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Molecular Oncology, EarlyView.Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source
A METHOD FOR ESTIMATING THE BACTERIA IN THE CIRCULATING BLOOD IN RABBITS [PDF]
, 1914 Carroll G. Bull
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