Results 51 to 60 of about 1,533,449 (332)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Listeriosis in a Rabbit [PDF]

open access: yesVeterinary Pathology, 1985
may be the possible cause of duplicated parts.’ In either case, during subsequent development, internal rearrangements of cells and tissues must support the vital processes of the extra parts, and interesting aspects of regulation are seen in the present specimen.
G. L. Watson, M. G. Evans
openaire   +3 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

SUITABILITY OF ALTERNATIVES TO RECTAL TEMPERATURE MEASUREMENTS IN PET RODENTS, RABBITS AND FERRETS: A LITERATURE REVIEW

open access: yesSlovenian Veterinary Research, 2023
Body temperature is a vital parameter to assess the health of exotic animals. Rectal thermometry is a common way to measure body temperature in rodents, rabbits and ferrets and often considered the gold standard.
Jelle Stans
doaj   +1 more source

EUROPEAN REFERENCE METHOD FOR IN VIVO DETERMINATION OF DIET DIGESTIBILITY IN RABBITS

open access: yes, 2010
This paper describes a standardized method for in vivo determination of total digestibility in rabbits. This method was working out within the European Group on Rabbit Nutrition (EGRAN) which involves six laboratories from five countries (Belgium, France,
Pérez J.M   +6 more
semanticscholar   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Influence of light exposure during late incubation, early feeding, and litter access posthatch on the stress response and body weight gain in laying hen chicks

open access: yesJournal of Applied Poultry Research
SUMMARY: In-ovo sexing opens the door to on-farm hatching in the laying hen sector, but knowledge on the implications of different hatching system factors remains limited.
Catharina M.H. Broekmeulen   +5 more
doaj   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

open access: yesMolecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo   +8 more
wiley   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Tapeworm in Rabbits [PDF]

open access: yesNature, 1877
I WOULD suggest that the tapeworm referred to by Mr. G. J. Romanes is like the Bothriocephalus of man—perhaps a species of the same genus. This is not supposed to have a cystic state, but to be developed from a ciliated embryo taken into the system on raw or badly-cooked vegetables, which have been watered by sewage from cesspools, in which the eggs ...
openaire   +3 more sources

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