Brain Pathology, Volume 33, Issue 1, January 2023., 2023 There is no pharmacological treatment available to limit progressing neuronal death after cerebral ischemia. Here we show that targeting the interaction of GABAB receptors with CaMKII using a synthetic interfering peptide after an excitotoxic insult in cultured neurons or in brain slices from MCAO‐treated mice restored downregulated GABAB receptor ...
Karthik Balakrishnan +7 more
wiley +1 more source
Application of high-throughput sequencing to whole rabies viral genome characterisation and its use for phylogenetic re-evaluation of a raccoon strain incursion into the province of Ontario [PDF]
, 2017 Raccoon rabies remains a serious public health problem throughout much of the eastern seaboard of North America due to the urban nature of the reservoir host and the many challenges inherent in multi-jurisdictional efforts to administer co-ordinated and ...
Biek, Roman +4 more
core +1 more source
Production, characterization, and antigen specificity of recombinant 62-71-3, a candidate monoclonal antibody for rabies prophylaxis in humans [PDF]
, 2013 Rabies kills many people throughout the developing world every year. The murine monoclonal antibody (mAb) 62-71-3 was recently identified for its potential application in rabies postexposure prophylaxis (PEP).
Anthony R. Fooks +42 more
core +1 more source
Journal of NeuroVirology, 2005 There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind rabies virus and/or facilitate rabies virus entry into cells.
openaire +4 more sources
Elucidating the phylodynamics of endemic rabies virus in eastern Africa using whole-genome sequencing [PDF]
, 2015 Many of the pathogens perceived to pose the greatest risk to humans are viral zoonoses, responsible for a range of emerging and endemic infectious diseases.
Biek, Roman +13 more
core +1 more source
Rabies surveillance in bats in Northwestern State of São Paulo
Revista da Sociedade Brasileira de Medicina Tropical, 2014 Introduction Rabies is an important zoonosis that occurs in mammals, with bats acting as Lyssavirus reservoirs in urban, rural and natural areas.
Daiene Karina Azevedo Casagrande +9 more
doaj +1 more source
Vaccine-induced rabies in a red fox in Poland
Journal of Veterinary Research, 2022 Rabies as a zoonosis threatens public health worldwide. Several thousand people die each year of infections by the rabies virus (RABV). Oral rabies vaccination (ORV) of wildlife was successfully implemented in many European countries and led to rabies ...
Smreczak Marcin +5 more
doaj +1 more source
Novel Sylvatic Rabies Virus Variant in Endangered Golden Palm Civet, Sri Lanka
Emerging Infectious Diseases, 2011 Information is scarce about sylvatic rabies virus in Asia and about rabies in palm civets. We report a novel sylvatic rabies virus variant detected in a golden palm civet in Sri Lanka.
Takashi Matsumoto +6 more
doaj +1 more source
Expression of Interferon Gamma by a Recombinant Rabies Virus Strongly Attenuates the Pathogenicity of the Virus via Induction of Type I Interferon. [PDF]
, 2014 UNLABELLED: Previous animal model experiments have shown a correlation between interferon gamma (IFN-γ) expression and both survival from infection with attenuated rabies virus (RABV) and reduction of neurological sequelae.
Barkhouse, Darryll A +5 more
core +2 more sources
Structural Proteins of Rabies Virus [PDF]
Journal of Virology, 1971 Purified rabies virions, unlabeled or labeled with radioactive amino acids or d -glucosamine, were dissociated into their polypeptides by treatment with sodium dodecyl sulfate in a reducing environment and fractionated by electroiphoresis in sodium dodecyl sulfate-containing polyacrylamide gel. The molecular weights
Daniel Stanček +2 more
openaire +3 more sources