Results 101 to 110 of about 22,107 (146)

An evolutionarily conserved salt bridge stabilizes the active site for GTP hydrolysis in Rho GTPases. [PDF]

J Biol Chem
Marcus K, Schwabe M, Knihtila R, Mattos C.   +3 more
europepmc   +1 more source

A Rac-specific competitive inhibitor of guanine nucleotide binding reduces metastasis in triple-negative breast cancer. [PDF]

Cell Rep Med
Dilasser F, Rose L, Quemener A, Ferrandez Y, Hassoun D, Rousselle M, Bergereau H, Lambot SM, Anselmino LE, Trouillet C, Andre G, Maillasson M, Croyal M, Riviere M, Dubreuil D, Collet S, Souaze F, Campone M, Patsouris A, Mortier E, Marquez MM, Juin P, Lebreton J, Tessier A, Cherfils J, Loirand G, Sauzeau V.   +26 more
europepmc   +1 more source

Guanine Nucleotide Exchange Factors and Small GTPases: Their Regulation and Functions, Diseases, and Therapeutic Targets. [PDF]

MedComm (2020)
Lin Z, Ni C, Jiang H, Yang H, Deng L, Liu P, Li X, Yu Y, Li W, Wang R, Liao B, Kang J, Liu J, Wu X, Ren J, Zhao Y.   +15 more
europepmc   +1 more source

Reduced RhoGDI2 Expression Disrupts Centrosome Functions and Promotes Mitotic Errors. [PDF]

Cells
Tripathi M, Garbacki N, Willems J, Cobraiville G, Fillet M, Colige A, Deroanne CF.   +6 more
europepmc   +1 more source

Rac1 palmitoylation is required for cardiac stress adaptation and regulation of protein kinase A signaling. [PDF]

JCI Insight
Teuber JP, Scissors RE, Subramani A, Madamanchi N, Brody MJ.   +4 more
europepmc   +1 more source

Inhibitors of De Novo Guanylate Biosynthesis Enhance the Potency of MAPK Cascade Inhibitors Against Colorectal Cancer. [PDF]

Int J Mol Sci
Maslov AA, Trageser NH, Kichina JV, Elamir H, Gardner E, Teaman F, Vishwanath V, Dugas SM, Bianchi-Smiraglia A, Leonova KI, Gurova KV, Nikiforov MA, Kandel ES.   +12 more
europepmc   +1 more source

Syndecan-4 interacts directly with β-parvin and regulates the ILK-PINCH-β-parvin complex, the β-parvin-β-PIX-Rac1 axis, and cardiomyocyte geometry in a sex-dependent manner. [PDF]

Front Cell Dev Biol
Mathiesen SB, Støle TP, Romaine A, Lunde M, Martinsen M, Aronsen JM, Sjaastad I, Louch WE, Christensen G, Carlson CR.   +9 more
europepmc   +1 more source

Unfolding ARF and ARL GTPases: from biophysics to systems-level insights. [PDF]

Front Mol Biosci
Quirion L, Strakhova R, Smith MJ, Côté JF.   +3 more
europepmc   +1 more source

TAS1R3 Regulates GTPase Signaling in Human Skeletal Muscle Cells for Glucose Uptake. [PDF]

Int J Mol Sci
Hoolachan JM, Balakrishnan R, Merz KE, Thurmond DC, Veluthakal R.   +4 more
europepmc   +1 more source

A novel DCSTAMP antagonist impedes preosteoclast fusion via modulation of RAP1B-RAC1-mediated cytoskeletal remodeling. [PDF]

Exp Mol Med
Zhang Z, Tao Z, Zhang W, Zhang Z, Zhang X, Xu X, Yang B, Meng Y, Tao X, Zhou X.   +9 more
europepmc   +1 more source