Results 51 to 60 of about 121,250 (302)

L'élevage des petits ruminants en Martinique, Guadeloupe et Guyane : situation actuelle

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1991
Les petits ruminants représentent 57000 têtes en Martinique, 30000 en Guadeloupe et un millier en Guyane, répartis en unités inférieures, en moyenne, à 10 têtes par exploitation.
J.C. Tatareau   +6 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Characterization of Blood Energetic Profile of Bovines Designed for Slaughter

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
The research in meat production domain is based on determining the quality of muscle tissue, missing the data on the physiological status of the animals before slaughter.
Ancuţa Elena Coşuleanu
doaj  

Oxidative profiles of endurance horses racing different distances

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2014
Increased oxidative stress during prolonged endurance exercises may result in muscle damage, fatigue and decreased performance. An adequate stress response during training is critical to obtain improved results and high animal welfare standards.
R.F. Siqueira   +4 more
doaj   +1 more source

La chèvre de Mayotte : vers une reconnaissance de la race

open access: yes, 2021
Bien que possédant une variété de couleurs de robe, de longueurs de poils et de formes des cornes, la chèvre de Mayotte représente une population homogène.
INRAE - FRA   +2 more
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

No Humans Involved The race-animal connection and its importance for Western philosophy

open access: yes, 2021
This thesis explores the connection between Western concepts of race and animality in the history of colonialism, transatlantic slavery and Enlightenment thought.
Tesselaar, N.
core  

Infrared Thermography Correlates with Lactate Concentration in Blood during Race Training in Horses

open access: yes, 2020
In horse racing the most acceptable way to objectively evaluate adaptation to increased exertion is to measure lactate blood concentration. However, this may be stressful for the horse, therefore, a simple, noninvasive procedure to monitor race progress ...
Olga Witkowska-Piłaszewicz   +3 more
core   +1 more source

A novel biomechanical analysis of gait changes in the MPTP mouse model of Parkinson’s disease [PDF]

open access: yes, 2015
Parkinson's disease (PD) is an age-associated neurodegenerative disorder hallmarked by a loss of mesencephalic dopaminergic neurons. Accurate recapitulation of the PD movement phenotype in animal models of the disease is critical for understanding ...
Geldenhuys, Werner   +9 more
core   +1 more source

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