Results 41 to 50 of about 514,952 (262)
Foucault Studies, 2011 In “Society Must Be Defended” Foucault examines 17th century race war discourse not so much in order to understand 20th century racism or concepts of race but primarily because it constitutes an historical example of an attempt to think power without a ...
Ladelle McWhorter
doaj +1 more source
Correlated Racing Evidence Accumulator Models [PDF]
Journal of Mathematical Psychology, 2019 Many models of response time that base choices on the first evidence accumulator to win a race to threshold rely on statistical independence between accumulators to achieve mathematical tractability (e.g., Brown & Heathcote, 2008; Logan et al., 2014; Van Zandt et al., 2000).
Angus Reynolds +3 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Merging race models and adaptive networks: A parallel race network [PDF]
Psychonomic Bulletin & Review, 2004 This article presents a generalization of race models involving multiple channels. The major contribution of this article is the implementation of a learning rule that enables networks based on such a parallel race model to learn stimulus-response associations. This model is called a parallel race network. Surprisingly, with a two-layer architecture, a
openaire +2 more sources
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Educational software design: applying models of learning
Research in Learning Technology, 1996 The model of learning adopted within this paper is the 'spreading ripples' (SR) model proposed by Race (1994). This model was chosen for two important reasons.
Stephen Richards
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Journal of International Medical Research, 2023 Objective To investigate the association between creatinine to cystatin C ratio (CCR) and bone mineral density (BMD) in middle-aged and older adults.
Zhenwei Wang +5 more
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