Results 171 to 180 of about 1,478 (205)

What place for ▼racecadotril?

Drug and Therapeutics Bulletin, 2013
Worldwide, there are about two billion cases of diarrhoeal disease every year and it is the second leading cause of death in children under 5 years of age, killing 1.5 million children annually.1 The most severe threat posed by diarrhoea is dehydration.
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Role of Probiotic and Racecadotril as an Adjuvant Therapy in Management of Acute Watery Diarrhea in Children

Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University
Objective: To see the role of nonspecific antidiarrheal agents as Probiotics and Racecadotril as an adjuvant therapy among children presenting with acute watery diarrhea Methodology: This cross-sectional comparative study was conducted in Pediatric ...
A. Pak, I. Sci, Lubna Asghar, Muhammad Usman, Rafia Gul, Aimen Tahir, Muhammad Usman Bashir, Irshad Hussain, Fasih Ul, Islam Hashmi   +9 more
semanticscholar   +1 more source

Improvement of bioavailability of poorly soluble racecadotril by solid dispersion with surface adsorption method: A case study

, 2021
Introduction: Biopharmaceutics classification system class II drugs show unpredictable bioavailability based on their solubility. Unfortunately, very few products were manufactured by this technique owing to their poor flowability and stability.
Bhaskar Daravath, G. Kumari
semanticscholar   +1 more source

Efficacy of Oral Racecadotril in Children with Acute Watery Diarrhea

Pakistan Armed Forces Medical Journal
Objective: To determine the efficacy of Racecadotril in treating acute watery diarrhea among children under 5 years of age attending Combined Military Hospital, Rawalpindi Pakistan. Study Design: Quasi-experimental study.
R. Tahir, Muhammad Tariq Nadeem, Hira Javed, Maryam Ijaz   +3 more
semanticscholar   +1 more source

A Comparative Study between Zinc Alone and Zinc with Racecadotril in Acute Watery Diarrhoea

Eastern Medical College journal
Background:Diarrhoea is one of the most common causes of morbidity and mortality in children under 5 years in the developing world. Racecadotril is a diesterified derivative of thiorphan. The objective of the study is to compare the effects of zinc alone
Abu Sufian, Atm Faruq Ahmed, A. Hossain, Mizanur Rahman Bhuyan, Sharmin Sultana, Debashis Chakrabarty, Mobarak Hossen, Ruhul Amin, Uzzal Kumar Ghosh   +8 more
semanticscholar   +1 more source

SIMULTANEOUS ANALYSIS OF OFLOXACIN, RACECADOTRIL AND ORNIDAZOLE IN PHARMACEUTICAL DOSAGE FORM BY RP-HPLC

Indian drugs
The combination of ofloxacin, ornidazole and racecadotril (Antof-OR) is used for the treatment of diarrhea. Due to the lack of a defined analytical approach upto this point, a rapid, accurate, repeatable, and easy HPLC method was developed to qualify and
P. Rajput, Sharib Khan, D. Das, Pooja A. Chawla   +3 more
semanticscholar   +1 more source

Comparison of racecadotril and loperamide in adults with acute diarrhoea

Alimentary Pharmacology & Therapeutics, 1999
MethodsA multicentre, randomized, double‐blind, double‐placebo, parallel‐group study was carried out to compare the efficacy, tolerability, and safety of racecadotril (100 mg three times daily) and loperamide (2 mg after each diarrhoeic stool) in 157 adults with acute diarrhoea.
J M, Vetel, H, Berard, N, Fretault, J M, Lecomte   +3 more
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Efficacy and tolerability of racecadotril in acute diarrhea in children

Gastroenterology, 2001
Oral rehydration therapy is the only treatment recommended by the World Health Organization in acute diarrhea in children. Antisecretory drugs available could not be used because of their side effects, except for racecadotril, which is efficient in acute diarrhea in adults.The efficacy and tolerability of racecadotril (1.5 mg/kg administered orally 3 ...
J P, Cézard, J F, Duhamel, M, Meyer, I, Pharaon, M, Bellaiche, C, Maurage, J L, Ginies, J M, Vaillant, J P, Girardet, T, Lamireau, A, Poujol, A, Morali, J, Sarles, J P, Olives, C, Whately-Smith, S, Audrain, J M, Lecomte   +16 more
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Racecadotril in the Treatment of Acute Watery Diarrhea in Children

New England Journal of Medicine, 2000
Racecadotril (acetorphan), an enkephalinase inhibitor with antisecretory and antidiarrheal actions, is an effective and safe treatment for acute diarrhea in adults and children. Whether treatment with racecadotril and oral rehydration therapy is more effective than treatment with oral rehydration alone in hospitalized children with acute watery ...
E, Salazar-Lindo, J, Santisteban-Ponce, E, Chea-Woo, M, Gutierrez   +3 more
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Racecadotril for childhood gastroenteritis: an individual patient data meta-analysis

Digestive and Liver Disease, 2011
Racecadotril is an antidiarrhoeal drug with intestinal antisecretory mechanism of action.To assess racecadotril efficacy as an adjunct to oral rehydration solution, against oral rehydration solution alone or with placebo in childhood acute gastroenteritis.Individual patient data meta-analysis following multilevel mixed models testing the significance ...
Philippe, Lehert, Gérard, Chéron, Guillermo Alvarez, Calatayud, Jean-Pierre, Cézard, Pedro Gutierrez, Castrellón, José-Manuel Meléndez, Garcia, Mar, Santos, M R, Savitha   +7 more
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