Results 171 to 180 of about 1,298 (203)
Efficacy of Racecadotril in Acute Watery Diarrhea in Children
Aqsa Noreen +2 more
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Cyclic Nucleotide Phosphodiesterase Families as Targets to Treat Pulmonary Arterial Hypertension: Beyond PDE5 Inhibitors? [PDF]
CellsWang L, Fischmeister R, Manoury B.
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Drugs, 2000
Racecadotril is an oral enkephalinase inhibitor used in the treatment of acute diarrhoea. It prevents the degradation of endogenous opioids (enkephalins), thereby reducing hypersecretion of water and electrolytes into the intestinal lumen. In a randomised double-blind study in 6 adult volunteers with castor oil-induced diarrhoea, racecadotril ...
A J, Matheson, S, Noble
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Racecadotril is an oral enkephalinase inhibitor used in the treatment of acute diarrhoea. It prevents the degradation of endogenous opioids (enkephalins), thereby reducing hypersecretion of water and electrolytes into the intestinal lumen. In a randomised double-blind study in 6 adult volunteers with castor oil-induced diarrhoea, racecadotril ...
A J, Matheson, S, Noble
+5 more sources
Hypersensitivity to racecadotril: a case report
European Journal of Pediatrics, 2006Hypersensitivity to racecadotril: a case ...
Nucera, Eleonora +5 more
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Racecadotril demonstrates intestinal antisecretory activity in vivo
Alimentary Pharmacology & Therapeutics, 1999Background Racecadotril (acetorphan), a potent enkephalinase inhibitor, protects endogenous enkephalins from degradation. Racecadotril exhibits experimental and clinical antidiarrhoeal activity without any effect on intestinal motility, suggesting selective antisecretory activity.
Primi, M.P. +4 more
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Racecadotril versus loperamide: antidiarrheal research revisited.
Digestive diseases and sciences, 2003Racecadotril is an enkephalinase inhibitor, presented as a purely antisecretory agent with advantages over the opiate-receptor agonist loperamide in the treatment of diarrhea. A critical review of the literature and the models used was performed. Although pretreatment with high doses of racecadotril reduced cholera toxin-induced secretion and although ...
S, Huighebaert +2 more
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Drug and Therapeutics Bulletin, 2013
Worldwide, there are about two billion cases of diarrhoeal disease every year and it is the second leading cause of death in children under 5 years of age, killing 1.5 million children annually.1 The most severe threat posed by diarrhoea is dehydration.
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Worldwide, there are about two billion cases of diarrhoeal disease every year and it is the second leading cause of death in children under 5 years of age, killing 1.5 million children annually.1 The most severe threat posed by diarrhoea is dehydration.
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Comparison of racecadotril and loperamide in adults with acute diarrhoea
Alimentary Pharmacology & Therapeutics, 1999MethodsA multicentre, randomized, double‐blind, double‐placebo, parallel‐group study was carried out to compare the efficacy, tolerability, and safety of racecadotril (100 mg three times daily) and loperamide (2 mg after each diarrhoeic stool) in 157 adults with acute diarrhoea.
J M, Vetel +3 more
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