Results 181 to 190 of about 1,298 (203)

Efficacy and tolerability of racecadotril in acute diarrhea in children

Gastroenterology, 2001
Oral rehydration therapy is the only treatment recommended by the World Health Organization in acute diarrhea in children. Antisecretory drugs available could not be used because of their side effects, except for racecadotril, which is efficient in acute diarrhea in adults.The efficacy and tolerability of racecadotril (1.5 mg/kg administered orally 3 ...
J P, Cézard, J F, Duhamel, M, Meyer, I, Pharaon, M, Bellaiche, C, Maurage, J L, Ginies, J M, Vaillant, J P, Girardet, T, Lamireau, A, Poujol, A, Morali, J, Sarles, J P, Olives, C, Whately-Smith, S, Audrain, J M, Lecomte   +16 more
openaire   +2 more sources

Racecadotril in the Treatment of Acute Watery Diarrhea in Children

New England Journal of Medicine, 2000
Racecadotril (acetorphan), an enkephalinase inhibitor with antisecretory and antidiarrheal actions, is an effective and safe treatment for acute diarrhea in adults and children. Whether treatment with racecadotril and oral rehydration therapy is more effective than treatment with oral rehydration alone in hospitalized children with acute watery ...
E, Salazar-Lindo, J, Santisteban-Ponce, E, Chea-Woo, M, Gutierrez   +3 more
openaire   +2 more sources

Racecadotril: a new approach to the treatment of diarrhoea

International Journal of Antimicrobial Agents, 2000
Since enkephalins were discovered in 1975, it has become clear that they play an antisecretory role in the gastrointestinal tract. Hence a rational research programme was directed at the development of a drug that would preserve these neurotransmitter peptides in the gut by preventing their inactivation.
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An overview of clinical studies with racecadotril in adults

International Journal of Antimicrobial Agents, 2000
Since preclinical studies had indicated the potential efficacy and tolerability of racecadotril for the treatment of diarrhoea in man, a series of studies was carried out to assess the clinical effects of racecadotril. These studies were also designed to evaluate whether racecadotril possessed the clinical properties that had been previously identified
openaire   +2 more sources

RP-LC Analysis and Hydrolytic Degradation Profile of Racecadotril

Chromatographia, 2008
A sensitive, stability-indicating liquid-chromatographic method for analysis of racecadotril in the presence of its degradation products has been developed and validated. Efficient chromatographic separation was achieved on a C18 column with a simple isocratic mobile phase—60:40 methanol–water. Quantification was by photo-diode array (PDA) detection at
Pawan K. Basniwal, Prabhat K. Srivastava, Surendra K. Jain, Deepti Jain   +3 more
openaire   +1 more source

Racecadotril

Reactions Weekly, 2022
openaire   +1 more source

Spectrophotometric and spectrofluorimetric methods for determination of Racecadotril.

Pakistan journal of pharmaceutical sciences, 2011
Two accurate and sensitive spectrophotometric and spectrofluorimetric methods were developed for determination of Racecadotril. In the first method reduction of Fe3+ into Fe2+ in presence of o-phenanthroline by Racecadotril to form a stable orange-red ferroin chelate [Fe-(Phen)3]2+ was the basis for its determination.
Nouruddin Wageih, Ali, Mohammed Refaat, Elghobashy, Mohammed Gamal, Mahmoud, Mohammed Abdelkawy, Mohammed   +3 more
openaire   +1 more source

Racecadotril

Reactions Weekly, 2006
openaire   +2 more sources

Loperamide/racecadotril

Reactions Weekly, 2021
openaire   +1 more source

Cimetidine/racecadotril

Reactions Weekly, 2022
openaire   +1 more source