Results 181 to 190 of about 1,478 (205)
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Racecadotril: a new approach to the treatment of diarrhoea
International Journal of Antimicrobial Agents, 2000Since enkephalins were discovered in 1975, it has become clear that they play an antisecretory role in the gastrointestinal tract. Hence a rational research programme was directed at the development of a drug that would preserve these neurotransmitter peptides in the gut by preventing their inactivation.
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An overview of clinical studies with racecadotril in adults
International Journal of Antimicrobial Agents, 2000Since preclinical studies had indicated the potential efficacy and tolerability of racecadotril for the treatment of diarrhoea in man, a series of studies was carried out to assess the clinical effects of racecadotril. These studies were also designed to evaluate whether racecadotril possessed the clinical properties that had been previously identified
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RP-LC Analysis and Hydrolytic Degradation Profile of Racecadotril
Chromatographia, 2008A sensitive, stability-indicating liquid-chromatographic method for analysis of racecadotril in the presence of its degradation products has been developed and validated. Efficient chromatographic separation was achieved on a C18 column with a simple isocratic mobile phase—60:40 methanol–water. Quantification was by photo-diode array (PDA) detection at
Pawan K. Basniwal +3 more
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Spectrophotometric and spectrofluorimetric methods for determination of Racecadotril.
Pakistan journal of pharmaceutical sciences, 2011Two accurate and sensitive spectrophotometric and spectrofluorimetric methods were developed for determination of Racecadotril. In the first method reduction of Fe3+ into Fe2+ in presence of o-phenanthroline by Racecadotril to form a stable orange-red ferroin chelate [Fe-(Phen)3]2+ was the basis for its determination.
Nouruddin Wageih, Ali +3 more
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