A study on the AMACR catalysed elimination reaction and its application to inhibitor testing [PDF]
, 2015 α-Methylacyl-CoA racemase (AMACR; P504S) catalyses a key step in the degradation of branched-chain fatty acids and is important for the pharmacological activation of Ibuprofen and related drugs. Levels of AMACR are increased in prostate and other cancers,
James, Tony D. +8 more
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Subsequence-based feature map for protein function classification [PDF]
, 2008 Automated classification of proteins is indispensable for further in vivo investigation of excessive number of unknown sequences generated by large scale molecular biology techniques.
Atalay V. +3 more
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The influence of manufacture on the free D-amino acid content of Cheddar cheese [PDF]
, 2018 t
Albert, Csilla +3 more
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Exploration of Metagenomic Racemases for Biosynthetic Cascades [PDF]
Biocatalysis becomes more and more appealing to industry due to its inherent ability to address contemporary demands for ecological, stereoselective synthesis from benign and biologically sourced materials, like amino acids.
Poschenrieder, Silvan Wolf
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Accumulation of malic acid and other industrially important organic acids by aspergillus tubingensis AN1257 / Produção biotecnológica de ácido málico por Aspergillus Tubingensis AN1257 [PDF]
, 2020 Organic acids act as acidifiers which improve sensorial characteristics of beverages, contributing to color, aroma, and taste. Malic acid is one of the industrially important acidifiers, and is also applied in metal cleaning.
Coelho, Suedali Villas Bôas +2 more
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Quantitative comparison of catalytic mechanisms and overall reactions in convergently evolved enzymes : implications for classification of enzyme function [PDF]
, 2010 The authors thank the National Institutes of Health (NIH R01 GM60595 to PCB) and the Scottish Universities Life Sciences Alliance (SULSA to JBOM) for funding.Functionally analogous enzymes are those that catalyze similar reactions on similar substrates ...
Daniel E. Almonacid +124 more
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UNVEILING NOVEL ASPECTS OF D-AMINO ACID METABOLISM IN THE MODEL BACTERIUM PSEUDOMONAS PUTIDA KT2440 [PDF]
, 2015 D-amino acids (D-AAs) are the α-carbon enantiomers of L-amino acids (L- AAs), the building blocks of proteins in known organisms. It was largely believed that D-AAs are unnatural and must be toxic to most organisms, as they would compete with the L ...
Radkov, Atanas D.
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A Review on Biological Catalysts in Organic Synthesis [PDF]
, 2016 The application of biocatalysts for the synthesis of novel compounds has attracted increasing attention over the past few years and consequently, high demands have been placed on the identification of new biocatalysts for organic synthesis. The catalysis
Ayuk, E.L., Okoro, U.C, Ugwu, M.O.
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Strukturelle und biochemische Charakterisierung von PhzF-artigen Isomerasen in Pseudomonas aeruginosa PA14 [PDF]
P. aeruginosa is an opportunistic pathogen that causes severe infections in cystic fibrosis and immunocompromised patients. Due to its resistance against many classes of antibiotics, adequate treatment of those patients is very difficult.
Schneider, Philipp Wilhelm
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O uso de enzimas presentes na água de coco Cocos nucifera L para a produção de esqueletos de natureza anti-inflamatória [PDF]
, 2016 Uma das grandes dificuldades encontradas hoje em dia é a capacidade de se produzir algo sem causar tantos prejuízos ao ambiente. Muitos fármacos produzidos através do método convencional utilizam várias rotas químicas que necessitam de solventes ...
Souza, Paulo Roni
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