Results 31 to 40 of about 594 (100)

Experimental evidence of d‐glutamate racemase activity in the uncultivated bacterium Candidatus Saccharimonas aalborgensis

Environmental Microbiology, Volume 26, Issue 4, April 2024.
Bacteria from the uncultivated Candidate Phyla Radiation (CPR) dominate various habitats, despite possessing limited metabolic capacities. These bacteria have incomplete sets of enzymes, which include pathways for producing structures that are essential for life. This supports the hypothesis of moonlighting activities in the remaining enzymes.
Marcos Peñalver, Alberto Paradela, César Palacios‐Cuéllar, M. Graciela Pucciarelli, Francisco García‐del Portillo   +4 more
wiley   +1 more source

EXPLORING THE BIOSYNTHESIS, FUNCTION, AND DETECTION OF THE NICKEL-PINCER NUCLEOTIDE COFACTOR [PDF]

Thesis (Ph.D.)--Michigan State University. Chemistry - Doctor of Philosophy, 2024The nickel-pincer nucleotide (NPN) cofactor is an organometallic cofactor critical for the activity of lactate racemase (LarA) and other racemases and epimerases.
Nevarez, Jorge Luis
core   +1 more source

Biochemical Tools for NMR Structural Elucidation of Peptides and Investigations of Cofactor-Independent Racemases and Epimerases

Proteins and peptides produced by the ribosome are initially composed of the 20 proteinogenic amino acids, 19 of which are chiral and have an L-configuration. One class of ribosomally synthesized peptides of interest are called bacteriocins. Bacteriocins
Lamer, Tess D.
core   +1 more source

Chemo-enzymatic synthesis of NPN cofactor taking advantage of ADP-ribosyl cyclase and LarC cyclometallase promiscuous activities

The nickel-pincer nucleotide cofactor (NPN) is a widespread organometallic cofactor required for lactate racemase (LarA) and for α-hydroxy acid racemases and epimerases of the LarA superfamily.
Strilets, Dmytro, Vucko, Timothe, Soumillion, Patrice, Desguin, Benoît, Strilets, Dmytro; id_orcid, Vincent, Stéphane P, Vincent, Stephane   +6 more
core   +1 more source

Mechanistic studies on UDP-N-acetylglucosamine 2-epimerase

, 1999
The bacterial enzyme UDP-N-acetylglucosamine 2-epimerase (UDP-GlcNAc 2- epimerase) catalyzes the interconversion between the sugar nucleotide UDP-N-acetylglucosamine (UDP-GlcNAc) and its C-2" epimer UDP-N-acetylmarinbsamine (UDP-ManNAc).
Sala, Rafael F.
core   +1 more source

Mechanistic investigations of enzyme-catalyzed peptide and carbohydrate epimerization

, 2004
The inversion of stereochemistry in biomolecules is catalyzed by enzymes called racemases and epimerases. One such epimerase, isolated from the venom of the funnel-web spider Agelenopsis aperta, interconverts two peptide neurotoxins that differ only by
Murkin, Andrew Stewart
core   +1 more source

Exploration and characterization of a superfamily of nickel-dependent hydroxy acid racemases and epimerases

Hydroxy acids (HAs) are organic carboxylic acids omnipresent in the living world, and are essential to various industries, including food, cosmetics, and pharmaceuticals.
Urdiain-Arraiza, Julian
core  

Les racémases et épimérases d'acides aminés (l'exemple de la TcPRAC comme cible pour le développement d'une thérapie contre l'infection par Trypanosoma cruzi)

, 2007
Le Trypanosoma cruzi est l agent étiologique de la Maladie de Chagas, pathologie affectant 20 millions de personnes en Amérique latine. Les traitements actuels sont inadéquats, le développement de nouvelles cibles thérapeutiques est essentiel. Nous avons
GOYTIA, Maïra, MINOPRIO, Paola
core  

Common catalytic features among cofactor independent racemases and epimerases: A computational perspective

UPDALP
Stenta, Marco, Altoe, Piero, Dal Peraro, Matteo, Garavelli, Marco, Bottoni, Andrea   +4 more
core  

The Engineering, Expression, and Immobilization of Epimerases for D-allulose Production. [PDF]

Int J Mol Sci, 2023
Tan JH, Chen A, Bi J, Lim YH, Wong FT, Ow DS.   +5 more
europepmc   +1 more source