Results 1 to 10 of about 13,885 (249)

Post-duplication charge evolution of phosphoglucose isomerases in teleost fishes through weak selection on many amino acid sites [PDF]

BMC Evolutionary Biology, 2007
Background The partitioning of ancestral functions among duplicated genes by neutral evolution, or subfunctionalization, has been considered the primary process for the evolution of novel proteins (neofunctionalization).
Sato Yukuto, Nishida Mutsumi
doaj   +3 more sources

Label-free quantitative proteomics analysis of producer and non-producer Chinese Hamsters Ovary (CHO) cells under ER stress conditions

Current Research in Biotechnology, 2023
Chinese Hamster Ovary (CHO) cells are the most commonly used host cell line used in the biopharmaceutical industry for the production of biotherapeutics.
David Ryan, Christiana-Kondylo Sideri, Michael Henry, Esen Efeoglu, Paula Meleady   +4 more
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The amino acid sequence of rabbit muscle triose phosphate isomerase [PDF]

FEBS Letters, 1973
The amino acid sequence of rabbit muscle triose phosphate isomerase was deduced by characterizing peptides that overlap the tryptic peptides. Thiol groups were modified by oxidation, carboxymethylation or aminoen. About 50 peptides that provided information about overlaps were isolated; the peptides were mostly characterized by their compositions and N-
Corran, P.H., Waley, S.G.
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The phycoerythrobilin isomerization activity of MpeV in Synechococcus sp. WH8020 is prevented by the presence of a histidine at position 141 within its phycoerythrin-I β-subunit substrate

Frontiers in Microbiology, 2022
Marine Synechococcus efficiently harvest available light for photosynthesis using complex antenna systems, called phycobilisomes, composed of an allophycocyanin core surrounded by rods, which in the open ocean are always constituted of phycocyanin and ...
Lyndsay A. Carrigee, Lyndsay A. Carrigee, Jacob P. Frick, Xindi Liu, Jonathan A. Karty, Jonathan C. Trinidad, Irin P. Tom, Xiaojing Yang, Louison Dufour, Frédéric Partensky, Wendy M. Schluchter   +10 more
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Myricetin, the main flavonoid in Syzygium cumini leaf, is a novel inhibitor of platelet thiol isomerases PDI and ERp5 [PDF]

, 2020
Background: Flavonoids have been characterized as a prominent class of compounds to treat thrombotic diseases through the inhibition of thiol isomerases. Syzygium cumini is a flavonoid-rich medicinal plant that contains myricetin and gallic acid.
Ayyanar, Banno, Bekendam, Bi, Chagas, Chagas, Chang, Chen, Chung, Dang, De Bona, Dutta-Roy, Essex, Essex, Essex, Ghoshal, Giamogante, Giamogante, Holbrook, Inoue, Jarvis, Jasuja, Jayakumar, Jordan, Kang, Kehrel, Kim, Lahav, Lakowicz, Lescano, Lin, Lu, Mangin, Masuda, Navarro-Nuñez, Park, Raffaelli, Raturi, Sharma, Sousa, Stopa, Taylor, Trnkova, Wang, Ware, Wendelboe   +45 more
core   +1 more source

Amino acid sequences around the cysteine residues of rabbit muscle triose phosphate isomerase [PDF]

Biochemical Journal, 1971
1. The nature of the subunits in rabbit muscle triose phosphate isomerase has been investigated. 2. Amino acid analyses show that there are five cysteine residues and two methionine residues/subunit. 3. The amino acid sequences around the cysteine residues have been determined; these account for about 75 residues. 4. Cleavage at the methionine residues
J C, Miller, S G, Waley
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Determination of the amino acid requirements for a protein hinge in triosephosphate isomerase [PDF]

Protein Science, 1998
AbstractWe have determined the sequence requirements for a protein hinge in triosephosphate isomerase. The codons encoding the hinge at the C‐terminus of the active‐site lid of triosephosphate isomerase were replaced with a genetic library of all possible 8, 000 amino acid combinations.
J, Sun, N S, Sampson
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Three amino acid substitutions contributing to thermostability of phosphoglucose isomerase in the Glanville fritillary butterfly

Insect Science, 2022
AbstractTemperature is one of the most important environmental factors that affect organisms, especially ectotherms, due to its effects on protein stability. Understanding the general rules that govern thermostability changes in proteins to adapt high‐temperature environments is crucial.
Yang, Jianing, Wang, Di, Liu, Hui, Wang, Lin, Jin, Ling, Ahola, Virpi, Xu, Chongren, Wang, Rongjiang   +7 more
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Insight into PreImplantation Factor (PIF*) mechanism for embryo protection and development: target oxidative stress and protein misfolding (PDI and HSP) through essential RIKP [corrected] binding site. [PDF]

PLoS ONE, 2014
Endogenous PIF, upon which embryo development is dependent, is secreted only by viable mammalian embryos, and absent in non-viable ones. Synthetic PIF (sPIF) administration promotes singly cultured embryos development and protects against their demise ...
Eytan R Barnea, David M Lubman, Yan-Hui Liu, Victor Absalon-Medina, Soren Hayrabedyan, Krassimira Todorova, Robert O Gilbert, Joy Guingab, Timothy J Barder   +8 more
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Crystal structures of Triosephosphate Isomerases from Taenia solium and Schistosoma mansoni provide insights for vaccine rationale and drug design against helminth parasites.

PLoS Neglected Tropical Diseases, 2020
Triosephosphate isomerases (TPIs) from Taenia solium (TsTPI) and Schistosoma mansoni (SmTPI) are potential vaccine and drug targets against cysticercosis and schistosomiasis, respectively.
Pedro Jimenez-Sandoval, Eduardo Castro-Torres, Rogelio González-González, Corina Díaz-Quezada, Misraim Gurrola, Laura D Camacho-Manriquez, Lucia Leyva-Navarro, Luis G Brieba, Luis G Brieba   +8 more
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