Results 11 to 20 of about 13,885 (249)

NmPin from the marine thaumarchaeote Nitrosopumilus maritimus is an active membrane associated prolyl isomerase. [PDF]

, 2016
We cordially thank Alma Rute for excellent technical assistance and the DFG (GRK 1431-1 and 1431-2) for financial support (PB). We thank the Microscope and Histology Facility of the University of Aberdeen for providing their equipment.
Bayer, Peter, Hoppstock, Lukas, Koenneke, Martin, Lederer, Christoph, Trusch, Franziska, Van West, Pieter   +5 more
core   +2 more sources

The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression

Hepatology, EarlyView., 2022
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro, Rut Espinosa‐Sotelo, Eva Crosas‐Molist, Macarena Herranz‐Itúrbide, Daniel Caballero‐Díaz, Ania Alay, Xavier Solé, Emilio Ramos, Teresa Serrano, María L. Martínez‐Chantar, Ulla G. Knaus, José M. Cuezva, Antonio Zorzano, Esther Bertran, Isabel Fabregat   +14 more
wiley   +1 more source

Compression of Large Sets of Sequence Data Reveals Fine Diversification of Functional Profiles in Multigene Families of Proteins: A Study for Peptidyl-Prolyl cis/trans Isomerases (PPIase)

Biomolecules, 2019
In this technical note, we describe analyses of more than 15,000 sequences of FK506-binding proteins (FKBP) and cyclophilins, also known as peptidyl-prolyl cis/trans isomerases (PPIases).
Andrzej Galat
doaj   +1 more source

Partial amino acid sequences of peptidyl-prolyl isomerases ofFusarium sporotrichioides

Journal of Biomedical Science, 1995
Peptidyl-proprylyl cis-trans isomerase (PPIase) activity was observed from crude extract of Fusarium sporotrichioides. Proteins from this fungi were separated by two-dimensional polyacrylamide gel electrophoresis and more than one thousand protein spots were separated. Two cytosolic PPIases were found by the N-terminal sequencing from the two separated
N., Fukaya, L.-P., Chow, Y., Sugiura, A., Tsugita, Y., Ueno, K., Tabuchi   +5 more
openaire   +2 more sources

Yellow Lupine Cyclophilin Transcripts Are Highly Accumulated in the Nodule Meristem Zone

Molecular Plant-Microbe Interactions, 2001
Cyclophilin (CyP) is one of the enzymes that act as peptidylprolyl cis-trans isomerases (EC 5.2.1.8). The cDNA and an intronless gene coding for cytosolic CyP have been isolated from yellow lupine.
Katarzyna Nuc, Przemysław Nuc, Ryszard Słomski   +2 more
doaj   +1 more source

Peptidyl-prolyl cis-trans isomerases (immunophilins) and their roles in parasite biochemistry, host-parasite interaction and antiparasitic drug action. [PDF]

, 2006
Immunophilin is the collective name given to the cyclophilin and FK506-binding protein (FKBP) families. As the name suggests, these include the major binding proteins of certain immunosuppressive drugs: cyclophilins for the cyclic peptide cyclosporin A ...
Adams, Aliberti, Alphey, Angus Bell, Antony P. Page, Argaet, Banerjee, Banumathy, Belfiore, Bell, Bell, Bell, Berriman, Blumenthal, Blumenthal, Borel, Bozdech, Braun, Bua, Carlton, Chakraborty, Chakraborty, Chappell, Chappell, Cianciotto, Cohen, Colgan, Dao-Thi, Denkers, Dobson, Dolinski, Dornan, Dornan, Dutta, Fischer, Florens, Galat, Galat, Gavigan, Gavigan, Gilleard, Golding, Hacker, Hall, High, Hirtzlin, Hong, Hope, Kamath, Kay, Ke, Khattab, Kiang, Klinkert, Klinkert, Knobloch, Kumar, Kumar, Kumar, Le Roch, Lightowlers, Lorberg, Ma, Ma, Ma, Matsuda, McLauchlan, Mikol, Monaghan, Monaghan, Moro, Osman, Ostoa-Saloma, Oz, Page, Page, Page, Page, Page, Page, Page, Paul Monaghan, Pelle, Pereira, Peterson, Picken, Pratt, Rascher, Reddy, Riggs, Rossi, Shirane, Silverman, Taylor, Tuo, Valle, Wang, Weiwad, Williams, Yarovinsky, Yu, Zorio   +101 more
core   +1 more source

PrsA2 (CD630_35000) of Clostridioides difficile Is an Active Parvulin-Type PPIase and a Virulence Modulator

Frontiers in Microbiology, 2018
Clostridioides difficile is the main cause for nosocomial antibiotic associated diarrhea and has become a major burden for the health care systems of industrial countries.
Can Murat Ünal, Can Murat Ünal, Mareike Berges, Nathiana Smit, Cordelia Schiene-Fischer, Christina Priebe, Till Strowig, Dieter Jahn, Dieter Jahn, Michael Steinert, Michael Steinert, Michael Steinert   +11 more
doaj   +1 more source

Mammalian l‐to‐d‐amino‐acid‐residue isomerase from platypus venom

FEBS Letters, 2006
The presence of d‐amino‐acid‐containing polypeptides, defensin‐like peptide (DLP)‐2 and Ornithorhyncus venom C‐type natriuretic peptide (OvCNP)b, in platypus venom suggested the existence of a mammalian d‐amino‐acid‐residue isomerase(s) responsible for the modification of the all‐l‐amino acid precursors.
Torres, A. M., Tsampazi, M., Tsampazi, C., Kennett, E. C., Belov, K., Geraghty, D. P., Bansal, P. S., Alewood, P. F., Kuchel, P. W.   +8 more
openaire   +3 more sources

Plant Triose Phosphate Isomerase Isozymes [PDF]

Plant Physiology, 1984
We report the first complete purifications of the cytosolic and plastid isozymes of triose phosphate isomerase (TPI; EC 5.3.1.1) from higher plants including spinach (Spinacia oleracea), lettuce (Lactuca sativa), and celery (Apium graveolens). Both isozymes are composed of two isosubunits with approximate molecular weight of 27,000; in spinach and ...
E, Pichersky, L D, Gottlieb
openaire   +2 more sources

LUD, a new protein domain associated with lactate utilization. [PDF]

, 2013
BackgroundA novel highly conserved protein domain, DUF162 [Pfam: PF02589], can be mapped to two proteins: LutB and LutC. Both proteins are encoded by a highly conserved LutABC operon, which has been implicated in lactate utilization in bacteria. Based on
Aravind, L, Axelrod, Herbert L, Bakolitsa, Constantina, Bateman, Alex, Coggill, Penelope C, Eberhardt, Ruth Y, Godzik, Adam, Hwang, William C, Pascual, Jaime, Peterson, Scott N, Punta, Marco, Rawlings, Neil D, Sedova, Mayya   +12 more
core   +2 more sources