Results 41 to 50 of about 632 (113)

MOESM1 of A food-grade expression system for d-psicose 3-epimerase production in Bacillus subtilis using an alanine racemase-encoding selection marker

, 2017
Additional file 1: Figure S1. The isolation of B. subtilis 1A751D1. Table S1. Strains and plasmids used in this study. Table S2. Primers used in this study.
Jingqi Chen, Zhaoxia Jin, Yuanming Gai, Jibin Sun, Dawei Zhang   +4 more
openaire   +1 more source

The chemistry and evolution of enzyme function: isomerases as a case study

, 2015
The study of the evolution of proteins has been traditionally undertaken from a sequence and structural point of view. However any attempt to understand how protein function changes during evolution benefits from consistent definitions of function and ...

core   +2 more sources

EXPLORING THE BIOSYNTHESIS, FUNCTION, AND DETECTION OF THE NICKEL-PINCER NUCLEOTIDE COFACTOR

Thesis (Ph.D.)--Michigan State University. Chemistry - Doctor of Philosophy, 2024The nickel-pincer nucleotide (NPN) cofactor is an organometallic cofactor critical for the activity of lactate racemase (LarA) and other racemases and epimerases.
Nevarez, Jorge Luis
core   +2 more sources

Chemo-enzymatic synthesis of NPN cofactor taking advantage of ADP-ribosyl cyclase and LarC cyclometallase promiscuous activities

The nickel-pincer nucleotide cofactor (NPN) is a widespread organometallic cofactor required for lactate racemase (LarA) and for α-hydroxy acid racemases and epimerases of the LarA superfamily.
Strilets, Dmytro, Vucko, Timothe, Soumillion, Patrice, Desguin, Benoît, Strilets, Dmytro; id_orcid, Vincent, Stéphane P, Vincent, Stephane   +6 more
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Les racémases et épimérases d'acides aminés (l'exemple de la TcPRAC comme cible pour le développement d'une thérapie contre l'infection par Trypanosoma cruzi)

, 2007
Le Trypanosoma cruzi est l agent étiologique de la Maladie de Chagas, pathologie affectant 20 millions de personnes en Amérique latine. Les traitements actuels sont inadéquats, le développement de nouvelles cibles thérapeutiques est essentiel. Nous avons
GOYTIA, Maïra, MINOPRIO, Paola
core  

Mechanistic studies on UDP-N-acetylglucosamine 2-epimerase

, 1999
The bacterial enzyme UDP-N-acetylglucosamine 2-epimerase (UDP-GlcNAc 2- epimerase) catalyzes the interconversion between the sugar nucleotide UDP-N-acetylglucosamine (UDP-GlcNAc) and its C-2" epimer UDP-N-acetylmarinbsamine (UDP-ManNAc).
Sala, Rafael F.
core  

Mechanistic investigations of enzyme-catalyzed peptide and carbohydrate epimerization

, 2004
The inversion of stereochemistry in biomolecules is catalyzed by enzymes called racemases and epimerases. One such epimerase, isolated from the venom of the funnel-web spider Agelenopsis aperta, interconverts two peptide neurotoxins that differ only by
Murkin, Andrew Stewart
core  

Common catalytic features among cofactor independent racemases and epimerases: A computational perspective

UPDALP
Stenta, Marco, Altoe, Piero, Dal Peraro, Matteo, Garavelli, Marco, Bottoni, Andrea   +4 more
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The Engineering, Expression, and Immobilization of Epimerases for D-allulose Production. [PDF]

Int J Mol Sci, 2023
Tan JH, Chen A, Bi J, Lim YH, Wong FT, Ow DS.   +5 more
europepmc   +1 more source

A Novel Epimerase Catalyzing Multiple Isomerization of Amino Acid Residues of Ribosomal Peptide

Salinipeptins, grisemycin, and cypemycin are ribosomally synthesized and post-translationally modified peptides (RiPPs). Among these, salinipeptins were reported to comprise 22 amino acid residues with multiple D-amino acids, and its biosynthetic gene ...
Xiao, Wanlu
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