Results 21 to 30 of about 746 (128)
Journal of Bacteriology, 1993 We have found that Pseudomonas putida ATCC 17642 cells grown in a medium containing D-threonine as the sole nitrogen source produce an enzyme that catalyzes epimerization of threonine. Proton nuclear magnetic resonance analysis of the enzyme reaction in deuterium oxide clearly showed epimerization from L- to D-allo-threonine and also from D- to L-allo ...
Y H, Lim +3 more
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Advances in enantioselective resolution applying preferential crystallization and enzymatic racemization [PDF]
, 2021 Enantiomers are pairs of identical chiral molecules that have different spatial arrangement. They present similar physical and chemical properties, but can interact differently in living organisms.
Carneiro, T.
core +2 more sources
Potential of Biocatalysis in Pharmaceuticals [PDF]
, 2020 Biocatalysis has been continuously evolving as an essential tool which is playing a significant role in the industrial synthesis of chemicals, active pharmaceuticals, pharmaceutical intermediates, etc.
Nigam, Vinod Kumar +2 more
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The chemistry and evolution of enzyme function: isomerases as a case study [PDF]
, 2014 The study of the evolution of proteins has been traditionally undertaken from a sequence and structural point of view. However any attempt to understand how protein function changes during evolution benefits from consistent definitions of function and ...
Martínez Cuesta, Sergio
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mBio, 2018 ABSTRACT Peptidoglycan is a sugar/amino acid polymer unique to bacteria and essential for division and cell shape maintenance. The d -amino acids that make up its cross-linked stem peptides are not abundant in nature and must be synthesized by bacteria de novo . d
George Liechti +5 more
openaire +3 more sources
Impact of CRISPR interference on strain development in biotechnology
Biotechnology and Applied Biochemistry, Volume 67, Issue 1, Page 7-21, January/February 2020., 2020 CRISPR interference drives metabolic engineering in biotechnology. Abstract Genetic perturbation systems are of great interest to redirect metabolic fluxes for value‐added production, as well as genetic screening for the development of new drugs, or to identify new targets for biotechnological applications. Here, we review CRISPR interference (CRISPRi),
Kerstin Schultenkämper +2 more
wiley +1 more source
Repetitive and Non-Repetitive DNA Sequences and a Speculation on the Origins of Evolutionary Novelty [PDF]
, 1971 Recent experimental information on DNA sequence repetition is reviewed, and the significance of both repetitive and non-repetitive sequence considered.
Britten, Roy J., Davidson, Eric H.
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Noise-induced symmetry breaking far from equilibrium and the emergence of biological homochirality [PDF]
, 2017 The origin of homochirality, the observed single-handedness of biological amino acids and sugars, has long been attributed to autocatalysis, a frequently assumed precursor for early life self-replication.
Biancalani, Tommaso +2 more
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Asymmetric and Selective Biocatalysis [PDF]
, 2019 This Issue contains one communication, six articles, and two reviews. The communication from Paola Vitale et al. represents a work where whole cells were used as biocatalysts for the reduction of optically active chloroalkyl arylketones followed by a ...
Mateo, Cesar, Palomo, Jose
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Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.Leptospira interrogans serovar Hardjo and Leptospira borgpetersenii serovar Hardjo are major bovine‐ and ovine‐adapted pathogens that differ markedly in genome content. To investigate early events during host exposure, we compared the survival of both species using an ovine peritoneal dialysis membrane chamber (DMC) model, which exposes leptospires to ...
Klaudia Dubniewicz +8 more
wiley +1 more source