Results 11 to 20 of about 775,231 (229)

A new twist in eutectic composition: deracemization of a racemic compound amino acid by Viedma ripening and temperature fluctuation. [PDF]

open access: yes, 2021
Viedma ripening and temperature fluctuation are processes based on solution phase racemization and dissolution-growth of racemic or scalemic conglomerates resulting in solid-phase deracemization.
José Eugenio, Ortíz, CRISTOBAL, VIEDMA
core   +3 more sources

Enabling direct preferential crystallization in a stable racemic compound system [PDF]

open access: yes, 2019
The preparative resolution by preferential crystallization (PC) of proxyphylline has been achieved despite the existence of a stable racemic compound. This is enabled through the careful selection of a solvent in which both the racemic compound and the ...
Brandel, Clément   +5 more
core   +3 more sources

Demystifying racemic natural products in the homochiral world [PDF]

open access: yes, 2022
Natural products possess structural complexity, diversity and chirality with attractive functions and biological activities that have significantly impacted drug discovery initiatives.
Nchiozem-Ngnitedem, Vaderament-A.   +8 more
core   +1 more source

Characterization of the conglomerate form of acetyl-dl-leucine by thermal analysis and solubility measurements [PDF]

open access: yes, 2012
Starting from a mixture of enantiomers in solution, crystallization can generate different types of crystals. In order to determine which type of crystal is obtained in the case of acetylleucine, an active pharmaceutical ingredient (API), analytical ...
B. Biscans   +9 more
core   +1 more source

Simultaneous Chiral Resolution of Two Racemic Compounds by Preferential Cocrystallization [PDF]

open access: yes, 2021
We tap into an unexplored area of preferential crystallization, being the first to develop simultaneous chiral resolution of two racemic compounds by preferential cocrystallization.We highlight how the two racemic compounds RS-mandelic ...
Oleksii, Shemchuk   +6 more
core   +1 more source

Discovery of Flavonoids from Scutellaria baicalensis with Inhibitory Activity Against PCSK 9 Expression: Isolation, Synthesis and Their Biological Evaluation

open access: yesMolecules, 2018
Nine flavonoids were isolated and identified from a chloroform-soluble fraction of the roots of Scutellaria baicalensis through a bioactivity-guided fractionation using a proprotein convertase subtilisin/kexin type 9 (PCSK9) monitoring assay in HepG2 ...
Piseth Nhoek   +7 more
doaj   +1 more source

Asymmetric racemic compound 141-A6. Raw diffraction data, 6ZX5

open access: yes, 2020
Raw diffraction data of asymmetric racemic compound 141 ...
Rypniewski, Wojciech   +3 more
core   +1 more source

Crystal structure of β-d,l-allose

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2015
The title compound, C6H12O6, a C-3 position epimer of glucose, was crystallized from an equimolar mixture of d- and l-allose. It was confirmed that d-allose (l-allose) formed β-pyranose with a 4C1 (1C4) conformation in the crystal.
Tomohiko Ishii   +4 more
doaj   +1 more source

Synthesis and Crystal Structure of Ethyl 5-(4-Bromophenyl)-7-methyl-3-oxo-2,3-dihidro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate

open access: yesMolbank, 2023
Thiazolopyrimidines are attractive to medical chemists as new antitumor agents due to their high inhibitory activity against the replication process of tumor cells and the easy modification of their structure by changing the number and nature of ...
Artem Agarkov   +5 more
doaj   +1 more source

Asymmetric racemic compound 143-D7b. Raw diffraction data, 7A9P

open access: yes, 2020
Raw diffraction data of asymmetric racemic compound 143 ...
Rypniewski, Wojciech   +3 more
core   +1 more source

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