Results 11 to 20 of about 23,430 (289)

Enabling Direct Preferential Crystallization in a Stable Racemic Compound System [PDF]

Molecular Pharmaceutics, 2019
The preparative resolution by preferential crystallization (PC) of proxyphylline has been achieved despite the existence of a stable racemic compound. This is enabled through the careful selection of a solvent in which both the racemic compound and the metastable conglomerate possess a low nucleation rate.
Harfouche, Lina, Brandel, Clément, Cartigny, Yohann, ter Horst, Joop, Coquerel, Gérard, Petit, Samuel   +5 more
openaire   +6 more sources

Searching for Conglomerate Cocrystals of the Racemic Compound Praziquantel [PDF]

Crystal Growth & Design, 2023
Contains fulltext : 302916.pdf (Publisher’s version ) (Open Access)
Peerapon Rapeenun, Charline J. J. Gerard, Clément Pinètre, Yohann Cartigny, Paul Tinnemans, René de Gelder, Adrian E. Flood, Joop H. ter Horst   +7 more
openaire   +4 more sources

A new twist in eutectic composition: deracemization of a racemic compound amino acid by Viedma ripening and temperature fluctuation.

, 2021
Viedma ripening and temperature fluctuation are processes based on solution phase racemization and dissolution-growth of racemic or scalemic conglomerates resulting in solid-phase deracemization.
José Eugenio, Ortíz, CRISTOBAL, VIEDMA
core   +2 more sources

(2S)-1,1-Dichloro-2-(2-chlorophenyl)-2-(4-chlorophenyl)ethane

Acta Crystallographica Section E, 2009
The title compound, C14H10Cl4, is easily crystallized while the other enantiomorph only forms an oil upon crystallization attempts. The title compound has a considerably higher density, ρ ≃ 1.562 Mg m−3 compared to the ...
Lars Eriksson, Tatiana Cantillana
doaj   +1 more source

Crystal structure and Hirshfeld surface analysis of new polymorph of racemic 2-phenylbutyramide

Acta Crystallographica Section E: Crystallographic Communications, 2019
A new polymorph of the title compound, C10H13NO, was obtained by recrystallization of the commercial product from a water/ethanol mixture (1:1 v/v). Crystals of the previously reported racemic and homochiral forms of 2-phenylbutyramide were grown from ...
Sergei Rigin, Beatrice Armijo, Arcadius V. Krivoshein, Marina Fonari, Tatiana Timofeeva   +4 more
doaj   +1 more source

Characterization of the conglomerate form of acetyl-dl-leucine by thermal analysis and solubility measurements [PDF]

, 2012
Starting from a mixture of enantiomers in solution, crystallization can generate different types of crystals. In order to determine which type of crystal is obtained in the case of acetylleucine, an active pharmaceutical ingredient (API), analytical ...
B. Biscans, Pena, Richard, S. Teychené, Estime, Nicolas, Biscans, Béatrice, R. Pena, N. Estime, Teychené, Sébastien, Autret, Jean Marie, J.M. Autret   +9 more
core   +1 more source

(2RS,4′RS)-3′-(3-Chloro-4-methoxyphenyl)-4′-phenyl-4′H-spiro[indene-2,5′-isoxazol]-1(3H)-one ethanol monosolvate

Acta Crystallographica Section E, 2011
The title compound, C23H17ClN2O3·C2H6O, is the stoichiometric 1:1 ethanol solvate of a racemic reaction product, which forms a conglomerate. The refined Flack parameter of 0.36 (3) indicates racemic twinning.
Adil Boughaleb, Hafid Zouihri, Said Gmouh, Abdelali Kerbal, Mohamed El yazidi   +4 more
doaj   +1 more source

X-ray Crystallography at 170 K of Racemic 2,2'-Dimethoxy-9,9'-biacridine and 1H NMR Study of 2,2'-Diacetoxy-9,9'-biacridine

Molecules, 1999
Three derivatives of 9,9'-biacridine, 2,2'-dihydroxy, 2,2'-dimethoxy and 2,2'-diacetoxy have been prepared. The crystal structure of racemic 2,2'-dimethoxy-9,9'-biacridine CHCl3 1:1 complex has been determined and shows an almost perpendicular ...
Albert Virgili, José Elguero, Marta Fierros, Concepción Foces- Foces, Antonio L. Llamas-Saiz, Jean-Pierre Galy, Tuan Lormier, Gérard Boyer   +7 more
doaj   +1 more source

Discovery of Flavonoids from Scutellaria baicalensis with Inhibitory Activity Against PCSK 9 Expression: Isolation, Synthesis and Their Biological Evaluation

Molecules, 2018
Nine flavonoids were isolated and identified from a chloroform-soluble fraction of the roots of Scutellaria baicalensis through a bioactivity-guided fractionation using a proprotein convertase subtilisin/kexin type 9 (PCSK9) monitoring assay in HepG2 ...
Piseth Nhoek, Hee-Sung Chae, Jagadeesh Nagarajappa Masagalli, Karabasappa Mailar, Pisey Pel, Young-Mi Kim, Won Jun Choi, Young-Won Chin   +7 more
doaj   +1 more source

Crystal structure and photoreactive behaviour of N,N-diisopropyl(p-phenylphenyl)glyoxylamide

Acta Crystallographica Section E: Crystallographic Communications, 2021
The title compound [systematic name: 2-([1,1′-biphenyl]-4-yl)-2-oxo-N,N-bis(propan-2-yl)acetamide], C20H23NO2 was synthesized and its photoreactive properties in the crystalline state and in acetonitrile solution were investigated.
Hisakazu Miyamoto, Hiroki Takahashi
doaj   +1 more source