Results 31 to 40 of about 51,541 (293)
Hepatology, EarlyView., 2022 Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode +16 more
wiley +1 more source
Advanced Robotics Research, EarlyView.An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy +13 more
wiley +1 more source
Comptes Rendus. Mathématique, 2011 In this Note, we introduce the category of Lie n -racks and generalize several results known on racks. In particular, we show that the tangent space of a Lie n -rack at the neutral element has a Leibniz n -algebra
openaire +3 more sources
Grip and Grasp: Lizard Claw Inspired Robotic Manipulators
Advanced Robotics Research, EarlyView.Our study identifies the most effective lizard claw shape for use as an end effector in a bioinspired robotic manipulator. By examining key geometric features and combining them into comparative indices, the Crotaphytus collaris claw is found to be the best fit.
Hyeon Lee +4 more
wiley +1 more source
Research on Meshing Characteristics of Trochoidal Roller Pinion Rack Transmission
Applied Sciences, 2022 As a precision transmission mechanism, the trochoidal roller pinion rack has been paid more and more attention in recent years, but its meshing characteristics have not been deeply explored.
Haiwei Wang, Lulu Li, Geng Liu
doaj +1 more source
Root‐Stimulated Movements in Mimosa Pudica for Biohybrid Robotic Systems
Advanced Robotics Research, EarlyView.This study demonstrates that thermal and electrical stimulation of Mimosa pudica root induces movement of the petiole and pinnules without direct stimulation of the aerial organs, thereby enabling a plant‐based robotic gripper and providing a foundation for the development of intelligent and sustainable systems.
Misao Sato +6 more
wiley +1 more source
Seismic Analysis of HFETR Spent Fuel Storage Rack Based on Parameterization-superelement Method
Yuanzineng kexue jishu, 2022 In order to solve the problems in the design of HFETR spent fuel storage rack, such as slow iterative design speed, long seismic analysis time and difficult multirack analysis, a combination of parameterization method and superelement method was ...
LIU Jinlong;ZHANG Hangzhou;WANG Shuai;SUN Zhijun;LONG Tao
doaj
Assessment of head loss coefficients for water turbine intake trash-racks by numerical modeling
Journal of Advanced Research, 2020 In this work, numerical simulations of fluid flow around trash-rack for different bar cross sections are conducted to investigate cross section influence on head losses.
Ivana Lučin +3 more
doaj +1 more source
Advanced Science, EarlyView.This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng +13 more
wiley +1 more source
Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2‐arm mRNA Platform
Advanced Science, EarlyView.We constructed a 2‐arm mRNA, characterized by a unique topology formed through the dimerization of two mRNA 3’ tails. The 2‐arm mRNA improves 3’ tail stability and resistance to nuclease degradation, resulting in an intracellular half‐life of up to 65 h. This method substantially enhances the translation capacity of mRNA drugs.
Xucong Teng +5 more
wiley +1 more source