Results 131 to 140 of about 691 (166)
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Functionally Distinct Nucleosome-Free Regions in Yeast Require Rad7 and Rad16 for Nucleotide Excision Repair

DNA Repair, 2008
In yeast, Rad7 and Rad16 are two proteins required for nucleotide excision repair (NER) of non-transcribed chromatin. They have roles in damage recognition, in the postincision steps of NER, and in ultraviolet-light-dependent histone H3 acetylation. Moreover, Rad16 is an ATP-ase of the SNF2 superfamily and therefore might facilitate chromatin repair by
Rolf Kraehenbuehl   +2 more
exaly   +4 more sources

The Yeast Rad7/Rad16/Abf1 Complex Generates Superhelical Torsion in DNA That Is Required for Nucleotide Excision Repair

DNA Repair, 2004
Nucleotide excision repair (NER) in eukaryotes removes DNA base damage as an oligonucleotide in a complex series of reactions. The nature of the dual incision reactions on either side of the damaged base has been extensively investigated. However, the precise mechanism of cleavage of the phosphodiester backbone of the DNA by the NER endonucleases and ...
Tom Owen-Hughes   +2 more
exaly   +3 more sources

Defective Excision of Pyrimidine Dimers and Interstrand DNA Crosslinks in rad7 and rad23 Mutants of Saccharomyces cerevisiae

Molecular Genetics and Genomics, 1982
Excision of pyrimidine dimers and interstrand DNA crosslinks was examined in the deletion mutants rad7-delta 1, rad23-delta 1, and rad7-delta 1 rad23-delta 1. These mutants remove pyrimidine dimers and crosslinks much less efficiently than the RAD+ strains; only 30-60% of pyrimidine dimers and 25-40% of crosslinks are removed even after prolonged ...
Satya Prakash, Louise Prakash
exaly   +3 more sources

Improvement of Measuring Methods and Instrumentation Concerning 222Rn Determination in Drinking Waters – RAD7 And LSC Technique Comparison

Applied Radiation and Isotopes, 2015
A procedure for the determination of (222)Rn in environmental water samples using liquid scintillation counting (LSC) was applied and optimized. A minimum detectable activity of 0.029Bql(-1) in a 20ml glass vial (10ml water sample mixed with 10ml of liquid scintillation cocktail) has been achieved during 300min of measurement time.
Ivana Stojković   +2 more
exaly   +3 more sources

High radon levels and adverse environmental conditions in using RAD7

Radiation Protection Dosimetry, 2023
Abstract Good response was observed in simultaneously using six RAD7 detectors at high radon concentrations, temperatures and relative humidity conditions. RAD7 detectors were tested in laboratory using radon chambers from 13 up to 59.8 kBq m−3, statistical analysis allows to distinct between counting errors and radon variation.
Arturo, Lopez   +2 more
openaire   +2 more sources

Crystal structure of the yeast Rad7-Elc1 complex and assembly of the Rad7-Rad16-Elc1-Cul3 complex

DNA Repair, 2019
Nucleotide excision repair (NER) is a versatile system that deals with various bulky and helix-distorting DNA lesions caused by UV and environmental mutagens. Based on how lesion recognition occurs, NER has been separated into global genome repair (GGR) and transcription-coupled repair (TCR).
Lan, Liu   +3 more
openaire   +2 more sources

RAD7 homologues contribute to Arabidopsis UV tolerance

Plant Science, 2018
Frequent exposure of plants to solar ultraviolet radiation (UV) results in damaged DNA. One mechanism of DNA repair is the light independent pathway Global Genomic Nucleotide Excision Repair (GG-NER), which repairs UV damaged DNA throughout the genome.
Triparna Lahari   +3 more
openaire   +2 more sources

Transposition of the gene cluster CYC1-OSM1-RAD7 in yeast

Journal of Molecular Biology, 1981
Abstract A mutant of the yeast Saccharomyces cerevisiae contains an increased amount of iso-1-cytochrome c because two copies of a segment, denoted COR, were transposed to a new position on chromosome VII, while the original COR region was retained at the normal position on chromosome X; this COR segment encompasses the CYC1, OSM1 and RAD7 loci which
J I, Stiles   +4 more
openaire   +2 more sources

The Effect of RAD7 Gene’s Null Mutation on Single-Cell Aging

Microbial Bioactive, 2022
Background: Although different theories and hypotheses were postulated for aging, molecular mechanisms of its regulations are still vastly unknown. In time, a post-mitotic cell ages with the aggregation of mutations within its genome and reach senescence. The DNA repair system that protects its genome also malfunctions with time.
openaire   +1 more source

Determination of radon concentration in water using RAD7 with RAD H2O accessories

AIP Conference Proceedings, 2015
In the last decade, the radon issue has become one of the major problems of radiation protection. Radon exposure occurs when using water for showering, washing dishes, cooking and drinking water. RAD7 and Rad H20 accessories were used in order to measure radon concentration in water sample.
M. F. I. Malik   +2 more
openaire   +1 more source

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