Results 61 to 70 of about 3,123,602 (300)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Arterial access site in the catheterisation lab : Is radial the way to go? [PDF]

open access: yes, 2013
Aim: With radial access increasing in popularity in the United States and the United Kingdom, this literature review explores whether radial access in coronary angiography and percutaneous coronary intervention is superior to femoral access, focusing on ...
Cassar, Mark Philip
core  

Investigating the graded-index influence on elastic responses of axisymmetric pressurized and heated thick-walled functionally graded material of cylindrical vessel

open access: yesForces in Mechanics, 2022
This article presents the influence of a graded-index on the elastic responses of an axisymmetric pressurized and heated thick-walled functionally graded material (FGM) cylindrical vessel under plane strain conditions.
Yihunie Mognhod Bezzie   +1 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

How to Start Your Radial Practice

open access: yes, 2021
Once committed to converting your practice to the radial approach, there are several tips and tricks that the authors suggest to improve your journey.
Evan Luther   +3 more
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Numerical solution of the two-dimensional Helmholtz equation with variable coefficients by the radial integration boundary integral and integro-differential equation methods [PDF]

open access: yes, 2012
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2012 Taylor & Francis.This paper presents new formulations of the boundary–domain integral equation (BDIE) and the boundary–domain integro-
Al-Jawary, MA, Wrobel, LC
core   +1 more source

Existence of infinitely many radial and non-radial solutions for quasilinear Schrödinger equations with general nonlinearity

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2017
In this paper, we prove the existence of many solutions for the following quasilinear Schrödinger equation \begin{equation*} -\Delta u - u\Delta(|u|^2) + V(|x|)u = f(|x|,u),\qquad x \in \mathbb{R}^N. \end{equation*} Under some generalized assumptions on $
Jianhua Chen   +3 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Influence of the constitutive flow law in FEM simulation of the Radial forging process [PDF]

open access: yes, 2013
Radial forging is a widely used forming process for manufacturing hollow products in transport industry. As the deformation of the workpiece, during the process, is a consequence of a large number of high-speed strokes, the Johnson-Cook constitutive law (
Gueye, Babacar   +3 more
core   +1 more source

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