Results 41 to 50 of about 100,965 (261)

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

P2.03 AORTIC, BUT NOT RADIAL PRESSURE GIVES A MODEL INDEPENDENT ESTIMATE OF CEREBRAL ARTERY CRITICAL CLOSING PRESSURE

Artery Research, 2013
Objectives: Cerebral artery critical closing pressure (CCP) is an estimated parameter with no single accepted method of calculation. Variation between methods could be significant.
M.O. Kim, M. Butlin, Y. Li, F. Wei, J. Wang, M. O’Rourke, A.P. Avolio   +6 more
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Doğal ve Plantasyonda Yetişen Kızılağaç (Alnus glutinosa L. Gaertner) Odunlarının Yıllık Halka Genişliği ve Lif Boyutlarının Radyal Değişimi

Düzce University Faculty of Forestry Journal of Forestry, 2016
Devam eden orman endüstri gelişiminin, yapısal odunun tüketiminin ve talebin artması nedeni ile hızlı büyüyen ağaçların plantasyonları endüstriyel odun hammaddesinin sürdürülebilirliği için önemli hale gelmektedir.
Kamile Tırak Hızal, Nurgün Erdin
doaj  

Effects on radial growth rate on basic density and compressive strength in 10-year-old Swietenia macrophylla planted in South Kalimantan, Indonesia

Forest Science and Technology
To evaluate the effect of radial growth rate on wood properties (basic density and compressive strength parallel to the grain under green conditions), standing tree characteristics (stem diameter, tree height, and stress-wave velocity of stems) were ...
Anak Agung Ayu Ratih Frismanti, Wiwin Tyas Istikowati, Ikumi Nezu, Jyunichi Ohshima, Shinso Yokota, Futoshi Ishiguri   +5 more
doaj   +1 more source

A Study of Variations in Radial Wrist Extensors

National Journal of Clinical Anatomy, 2019
Abstract Background and Aim Supernumerary muscles and tendons from extensor carpi radialis longus (ECRL) and extensor carpi radialis brevis (ECRB) are sometimes encountered during hand surgery. They include accessory muscles like extensor carpi radialis intermedius (ECRI), intertendinous slips (ITS) between the two muscles, or simple ...
Stelin Agnes Michael, Gaddam Vijaya Lakshmi   +1 more
openaire   +2 more sources

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Variation in wood density between mature sessile oak and English oak trees growing in different vegetation zones

Journal of Forest Science
Wood density is a fundamental functional trait influencing ecological adaptation, hydraulic safety, and timber utilisation in temperate hardwoods. This study investigated variation in wood density (12% moisture) across mature stands of two economically ...
Vladimír Gryc, Kyriaki Giagli, Sergei Mikhailov, Marko Stojanović, Dimitrios Tsalagkas, Hanuš Vavrčík, Petr Horáček   +6 more
doaj   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source