Results 41 to 50 of about 392,204 (294)

Effect of Radiation Defects on Thermo–Mechanical Properties of UO₂ Investigated by Molecular Dynamics Method

Metals, 2022
Nuclear fuel performance is deteriorated due to radiation defects. Therefore, to investigate the effect of irradiation-induced defects on nuclear fuel properties is essential.
Ziqiang Wang, Miaosen Yu, Chen Yang, Xuehao Long, Ning Gao, Zhongwen Yao, Limin Dong, Xuelin Wang   +7 more
doaj   +1 more source

Radiation tolerance of GaN: the balance between radiation-stimulated defect annealing and defect stabilization by implanted atoms

Journal of Physics D: Applied Physics, 2022
Abstract Realization of radiation-hard electronic devices that are able to work in harsh environments requires deep understanding of the processes of defect formation/evolution occurring in semiconductors bombarded by energetic particles.
A I Titov, K V Karabeshkin, A I Struchkov, P A Karaseov, A Azarov   +4 more
openaire   +3 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

CHANGES IN THERMALLY STIMULATED CONDUCTIVITY OF CsPbBr3 AND CsPbCl3 CRYSTALS EXPOSED TO X-RAY IRRADIATION

Електроніка та інформаційні технології
Introduction. CsPbBr3 and CsPbCl3 crystals remain among the most intensively studied materials. This is due to their high efficiency in solar cells, which currently exceeds 22%.
Bohdan Pavlyk, Roman Lys, Roman Gamernyk, Mykola Goydalo   +3 more
doaj   +1 more source

Characteristics of photodiodes with «intrinsic oxide — InSe» structure, irradiated with high-energy electrons [PDF]

Технологія та конструювання в електронній апаратурі, 2012
The article describes the research of the influence of electrons with an effective energy of 12 MeV in the 0,33–33 Mrad dose range on the electrical and photovoltaic properties of photodiodes with «intrinsic oxide — p-InSe» structure.
O. N. Sydor, O. A. Sydor, Z. D. Kovalyuk, V. I. Dubinko   +3 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Evolution of Scintillation and Electrical Characteristics of AlGaN Double-Response Sensors During Proton Irradiation

Sensors, 2019
Wide bandgap AlGaN is one of the most promising materials for the fabrication of radiation hard, double-response particle detectors for future collider facilities.
Tomas Ceponis, Kazimieras Badokas, Laimonas Deveikis, Jevgenij Pavlov, Vytautas Rumbauskas, Vitalij Kovalevskij, Sandra Stanionyte, Gintautas Tamulaitis, Eugenijus Gaubas   +8 more
doaj   +1 more source

Kinetic effects in cadmium antimonide crystals before and after gamma-irradiation

Фізика і хімія твердого тіла, 2020
The influence of large doses of 60Co gamma-quanta on the electrical properties of cadmium antimonide crystals with different electrical conductivity has been investigated.
S. A. Fedosov, D. A. Zakharchuk, Y. V. Кoval, L. V. Yashchynskiy, O. A. Urban   +4 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source