Results 71 to 80 of about 14,661,451 (396)

Risk Factors for Childhood Leukemia: Radiation and Beyond

Frontiers in Public Health, 2021
Childhood leukemia (CL) is undoubtedly caused by a multifactorial process with genetic as well as environmental factors playing a role. But in spite of several efforts in a variety of scientific fields, the causes of the disease and the interplay of ...
Janine-Alison Schmidt, Sabine Hornhardt, Friederike Erdmann, Friederike Erdmann, Isidro Sánchez-García, Ute Fischer, Joachim Schüz, Gunde Ziegelberger   +7 more
doaj   +1 more source

Microbiota- and Radiotherapy-Induced Gastrointestinal Side-Effects (MARS) Study: A Large Pilot Study of the Microbiome in Acute and Late-Radiation Enteropathy

Clinical Cancer Research, 2019
Purpose: Radiotherapy is important in managing pelvic cancers. However, radiation enteropathy may occur and can be dose limiting. The gut microbiota may contribute to the pathogenesis of radiation enteropathy.
M. Reis Ferreira, J. Andreyev, K. Mohammed, L. Truelove, S. Gowan, Jia V. Li, S. Gulliford, J. Marchesi, D. Dearnaley   +8 more
semanticscholar   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Targeted Dorsal Dentate Gyrus or Whole Brain Irradiation in Juvenile Mice Differently Affects Spatial Memory and Adult Hippocampal Neurogenesis

Biology, 2021
The cognitive consequences of postnatal brain exposure to ionizing radiation (IR) at low to moderate doses in the adult are not fully established. Because of the advent of pediatric computed tomography scans used for head exploration, improving our ...
Céline Serrano, Morgane Dos Santos, Dimitri Kereselidze, Louison Beugnies, Philippe Lestaevel, Roseline Poirier, Christelle Durand   +6 more
doaj   +1 more source

The Matrix Element Method and QCD Radiation

, 2011
The matrix element method (MEM) has been extensively used for the analysis of top-quark and W-boson physics at the Tevatron, but in general without dedicated treatment of initial state QCD radiation.
A. Freitas, J. Alwall, J. Alwall, O. Mattelaer   +3 more
core   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Mutational Signatures in Radiation-Induced Cancer: A Review of Experimental Animal and Human Studies

Biology
Ionizing radiation can damage DNA, leading to mutations, and is a risk factor for cancer. Based on the assumption that all radiation exposure poses a risk in linear proportion to its dose, ionizing radiation is considered a non-threshold carcinogen ...
Kazuhiro Daino, Chizuru Tsuruoka, Atsuko Ishikawa, Shizuko Kakinuma, Tatsuhiko Imaoka   +4 more
doaj   +1 more source

Germline DNA Retention in Murine and Human Rearranged T Cell Receptor Gene Coding Joints: Alternative Recombination Signal Sequences and V(D)J Recombinase Errors

Frontiers in Immunology, 2019
The genes coding for the antigenic T cell receptor (TR) subunits are assembled in thymocytes from discrete V, D, and J genes by a site-specific recombination process.
Justyna Mika, Sylwia Kabacik, Christophe Badie, Joanna Polanska, Serge M. Candéias   +4 more
doaj   +1 more source

Pathological effects of ionizing radiation: endothelial activation and dysfunction

Cellular and Molecular Life Sciences, 2018
The endothelium, a tissue that forms a single layer of cells lining various organs and cavities of the body, especially the heart and blood as well as lymphatic vessels, plays a complex role in vascular biology.
Bjorn Baselet, P. Sonveaux, S. Baatout, A. Aerts   +3 more
semanticscholar   +1 more source

Generation of Seed Magnetic Field around First Stars: the Biermann Battery Effect

, 2011
We investigate generation processes of magnetic fields around first stars. Since the first stars are expected to form anisotropic ionization fronts in the surrounding clumpy media, magnetic fields are generated by effects of radiation force as well as ...
Ando, Biermann, Blasi, Bromm, Clark, Fukugita, Gnedin, Greif, Hajime Susa, Kentaro Doi, Kulsrud, Machida, Machida, Maki, Maki, Nakamura, Nakano, Nakano, Navarro, Omukai, Omukai, Prada, Schleicher, Schleicher, Sethi, Sur, Tan, Vallée, Xu, Yoshida   +29 more
core   +1 more source