Results 81 to 90 of about 2,082,361 (307)
Laser-assisted spin-polarized transport in graphene tunnel junctions
, 2014 Keldysh nonequilibrium Green's function method is utilized to study theoretically the spin polarized transport through a graphene spin valve irradiated by a monochromatic laser field.
Berakdar, Jamal +2 more
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
In vitro study of radiosensitivity in colorectal cancer cell lines associated with Lynch syndrome
Frontiers in Public HealthIntroductionLynch syndrome patients have an inherited predisposition to cancer due to a deficiency in DNA mismatch repair (MMR) genes which could lead to a higher risk of developing cancer if exposed to ionizing radiation. This pilot study aims to reveal
Mingzhu Sun +13 more
doaj +1 more source
Environment International, 2019 Hot weather can exacerbate health conditions such as cardiovascular and respiratory diseases, and lead to heat stroke and death. In built up areas, temperatures are commonly observed to be higher than those in surrounding rural areas, due to the Urban ...
H.L. Macintyre, C. Heaviside
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Ultraviolet radiation effects [PDF]
Solar ultraviolet testing was not developed which will provide highly accelerated (20 to 50X) exposures that correlate to flight test data. Additional studies are required to develop an exposure methodology which will assure that accelerated testing can ...
Slemp, Wayne S.
core +1 more source
Probing optomechanical correlations between two optical beams down to the quantum level [PDF]
, 2008 Quantum effects of radiation pressure are expected to limit the sensitivity of second-generation gravitational-wave interferometers. Though ubiquitous, such effects are so weak that they haven't been experimentally demonstrated yet.
A. Heidmann +6 more
core +4 more sources
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Colorectal cancers associated with mismatch repair deficiency
Frontiers in MedicineThis review aims to summarize the latest updates in the prevention, diagnosis, treatment and management of colorectal cancers (CRCs) associated with mutation(s) or alteration(s) in the DNA mismatch repair (MMR) genes.
Mingzhu Sun +4 more
doaj +1 more source