Results 51 to 60 of about 2,059,339 (331)

Evolution of massive binary black holes [PDF]

open access: yes, 2001
Since many or most galaxies have central massive black holes (BHs), mergers of galaxies can form massive binary black holes (BBHs). In this paper, we study the evolution of massive BBHs in realistic galaxy models, using a generalization of techniques ...
Yu, Qingjuan
core   +3 more sources

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker   +7 more
wiley   +1 more source

Direct Observation of Cu Clusters and Dislocation Loops by Cs-Corrected STEM in Fe-0.6wt%Cu Alloy Irradiated in BR2

open access: yesMetals, 2022
The neutron irradiation of Fe-based fusion and fission reactor materials leads to an increase in ductile-to-brittle transition temperature with a decrease in upper shelf energy. It is well known that Cu content has a strong influence on the embrittlement
Hideo Watanabe   +3 more
doaj   +1 more source

Cosmic rays: direct measurements [PDF]

open access: yes, 2015
This paper is based on the rapporteur talk given at the 34$^{th}$ International Cosmic Ray Conference (ICRC), on August 6$^{th}$, 2015. The purpose of the talk and paper is to provide a summary of the most recent results from balloon-borne and space ...
Maestro, Paolo
core   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Research progress on irradiation effect of InP-based high electron mobility transistors

open access: yesHe jishu
Indium phosphide (InP)-based high electron mobility transistors (HEMTs) have been widely adopted in space communication systems such as satellites, manned spaceflight, and deep space exploration due to their high frequency and gain, and low noise ...
FANG Renfeng   +7 more
doaj   +1 more source

The effect of Laves phase on heavy-ion radiation response of Nb-containing FeCrAl alloy for accident-tolerant fuel cladding

open access: yesFundamental Research, 2022
As a promising candidate material for the accident tolerant fuel cladding in light water reactors, the Nb-containing FeCrAl alloy has shown outstanding out-of-pile service performance due to the Laves phase precipitation.
Hang Xu   +8 more
doaj   +1 more source

X-ray Flares from Markarian 501 [PDF]

open access: yes, 2004
Motivated by the recent finding of hierarchical X-ray flaring phenomenon in Mrk 421, we conducted a systematic search for X-ray flares from Mrk 501, another well-known TeV blazar, by making use of the rich {\em RXTE} archival database. We detected flares
Bottcher M.   +6 more
core   +4 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

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