Submillimeter and X-ray observations of an X Class flare [PDF]
The GOES X1.5 class flare that occurred on August 30,2002 at 1327:30 UT is one of the few events detected so far at submillimeter wavelengths. We present a detailed analysis of this flare combining radio observations from 1.5 to 212 GHz (an upper limit ...
A. Silva-Valio +45 more
core +4 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
High-Energy Spectral Complexity from Thermal Gradients in Black Hole Atmospheres
We show that Compton scattering of soft photons with energies near 100 eV in thermally stratified black-hole accretion plasmas with temperatures in the range 100 keV - 1 MeV can give rise to an X-ray spectral hardening near 10 keV. This could produce the
C. D. Dermer +17 more
core +1 more source
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Some new results on irradiation characteristics of synthetic quartz crystals and their application to radiation hardening [PDF]
The paper reports some new results on irradiation characteristics of synthetic quartz crystals and their application to radiation hardening. The present results show how the frequency shift in quartz crystals can be influenced by heat processing prior to
Bahadur, H., Parshad, R.
core +1 more source
Numerical Simulation of the Thermodependant Viscohyperelastic Behavior of Polyethylene Terephthalate Near the Glass Transition Temperature: Prediction of the Self-Heating During Biaxial Tension Test [PDF]
The poly ethylene terephthalate near the glass transition temperature highlights a strongly non linear elastic and viscous behaviour when biaxially stretched at high strain rates representative of the injection stretch blow moulding process. A non linear
Andrieu +29 more
core +6 more sources
Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa +10 more
wiley +1 more source
State of the Art of Laser Hardening and Cladding [PDF]
In this paper an overview is given about laser surface modification processes, which are developed especially with the aim of hardness improvement for an enhanced fatigue and wear behaviour.
Meijer, J., Partes, K., Vollertsen, F.
core +1 more source

