Results 141 to 150 of about 513,484 (358)

Focal Spot, Fall/Winter 1990 [PDF]

, 1990
https://digitalcommons.wustl.edu/focal_spot_archives/1056/thumbnail ...

core   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

White matter changes are correlated significantly with radiation dose. Observations from a randomized dose-escalation trial for malignant glioma (radiation therapy oncology group 83-02) [PDF]

, 1994
Benjamin W. Corn, David M. Yousem, Charles Scott, Marvin Rotman, Sucha O. Asbell, Diana F. Nelson, Linda Martin, Walter J. Curran   +7 more
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Focal Spot, Fall/Winter 1987 [PDF]

, 1987
https://digitalcommons.wustl.edu/focal_spot_archives/1047/thumbnail ...

core   +1 more source

USP10 Inhibits Ferroptosis via Deubiquinating POLR2A in Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study identifies USP10 as a novel deubiquitinase that antagonizes ferroptosis in head and neck squamous cell carcinoma (HNSCC). Mechanistically, USP10 directly stabilizes POLR2A protein through post‐translational deubiquitination, enabling POLR2A‐mediated transcriptional activation of SLC7A11, a key ferroptosis inhibitor.
Diekuo Zhang, Xueying Wang, Shanhong Lu, Yan Gao, Gangcai Zhu, Guo Li, Zongnan Yu, Junwei Hou, Helei Yan, Wenhui Yuan, Xin Zhang, Mien‐Chie Hung, Zhifeng Liu, Yong Liu   +13 more
wiley   +1 more source

Prognostic factors influencing the effect of irradiation in non-oat cell unresectable carcinoma of the lung. A randomized study by the radiation therapy oncology group

, 1979
C.A. Perez, K. Stanley, William Mietlowski, P. Rubin, Sebastian Krämer, L.W. Brady, R Pérez-Tamayo, S. Brown, Joseph P. Concannon, H. Gunter Seydel, Marvin Rotman, William J. Hanson   +11 more
openalex   +1 more source

interruptions adversely affect local control and survival with hyperfractionated radiation therapy of carcinomas of the upper respiratory and digestive tracts new evidence for accelerated proliferation from radiation therapy oncology group protocol 8313 [PDF]

, 1992
James D. Cox, Thomas F. Pajak, Víctor A. Marcial, Lawrence R. Coia, Mohammed Mohiuddin, Karen K. Fu, H. Selim, Roger W. Byhardt, Philip Rubin, H. Ortíz, Linda Martin   +10 more
openalex   +1 more source

Focal Spot, Fall 1976 [PDF]

, 1976
https://digitalcommons.wustl.edu/focal_spot_archives/1015/thumbnail ...

core   +1 more source

The LDH‐H3K18La‐Nur77 Axis Potentiates Immune Escape in Small Cell Lung Cancer

Advanced Science, EarlyView.
Lactate from SCLC tumors induces H3K18 lactylation in naïve CD8+ T cells, upregulating Nurr77 and enhancing tonic TCR signaling. This leads to T cell hyporesponsiveness to stimulation, impairing antitumor immunity and reducing immunotherapy efficacy.
Xiaoling Shang, Bo Cheng, Chenyue Zhang, Chenglong Zhao, Ruiqing Wang, Xun Zhang, Dizhi Jiang, Xinyu Zhang, Xinyue Ma, Hongyuan Mao, Zerun Li, Chenhan Huang, Tianzi Wang, Kaiyue Guo, Liwen Wang, Ning Tang, Haiyong Wang   +16 more
wiley   +1 more source

Improved survival duration in patients with unresected solitary brain metastasis using accelerated hyperfractionated radiation therapy at total doses of 54.4 gray and greater results of radiation therapy oncology group 85–28 [PDF]

, 1993
Barry E. Epstein, Charles Scott, William T. Sause, Marvin Rotman, Penny K. Sneed, Nora A. Janjan, Lawrence W. Davis, H. Selim, Mohammed Mohiuddin, Todd H. Wasserman, Walter J. Curran   +10 more
openalex   +1 more source