Results 121 to 130 of about 364,834 (265)

Clinical governance in radiation oncology. [PDF]

Rep Pract Oncol Radiother
Malicki J, Guedea F, Krengli M.
europepmc   +1 more source

RNF138‐Mediated Ubiquitination and Degradation of NS5 Restricts Tick‐Borne Encephalitis Virus Infection

Advanced Science, EarlyView.
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun, Weijing Yang, Hao Zhou, Shuai Li, Xin Jiang, Jianyang Gu, Wenyan Zhang   +6 more
wiley   +1 more source

Simulation training in radiation oncology. [PDF]

J Appl Clin Med Phys
Schell MC, Beavis AW, Brown DW, Milano M, O'Neill M, Yu Y, Pavord DC, Dunscombe P.   +7 more
europepmc   +1 more source

Antigen Spreading via Localized Administration Enhances Adoptive TCR‐T Cell Therapy in Pancreatic Cancer

Advanced Science, EarlyView.
Cancer vaccines face limitations in pancreatic cancer due to insufficient tumor antigens. This ionic liquid ILvax via local tumor delivery triggers robust cDC1‐dependent systemic anti‐tumor immunity. It boosts endogenous CD8+ T cells and optimizes adoptive TCR‐T function, providing a promising synergistic therapeutic strategy.
Junming Huang, Qin Wang, Zhuo Yao, Qing Wang, Yongtao Ji, Minqi Yang, Meng Wang, Shiyi Shao, Xinyu Zhao, Fu Zhang, Tingbo Liang, Qida Hu   +11 more
wiley   +1 more source

The Contemporary Role of Virtual and Augmented Reality in Radiation Oncology: A Review. [PDF]

Curr Oncol
Mohssine S, Pelland MÈ, Bedwani S, Roberge D.   +3 more
europepmc   +1 more source

Inhibition of KDEL Receptors Remodels the Tumor Microenvironment for T Cell Independent Tumor Regression

Advanced Science, EarlyView.
Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak, Hong Wang, Belinda Willard, Timothy A. Chan, William C Merrick, Zheng‐Rong Lu, Boaz Tirosh   +6 more
wiley   +1 more source

Artificial Intelligence for Predicting Immunotherapy Efficacy in Non-Small Cell Lung Cancer

Journal of Inflammation Research
Pingdong Cao,1 Xiao Jia,2 Yuqi Yang,1 Xi Wang,3 Jian Zhu,4 Xiaomei Li,1 Zhe Yang,1 Qiang Wen1 1Department of Radiation Oncology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Shandong First Medical University, Jinan ...
Cao P, Jia X, Yang Y, Wang X, Zhu J, Li X, Yang Z, Wen Q   +7 more
doaj  

Radiation oncology as a complex adaptive system. [PDF]

Front Oncol
Bakhtiari M.
europepmc   +1 more source

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

Advanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu, Shutao Zhang, Yumin Lin, Juyang Jiao, Zhiwei Fu, Qimin Hong, Ziyi Zhao, Xinhua Qu, Fei Su, Bing Yue   +9 more
wiley   +1 more source

Editorial: Innovative approaches in precision radiation oncology. [PDF]

Front Med (Lausanne)
Parchur AK, Yadav P.
europepmc   +1 more source