Results 101 to 110 of about 363,464 (264)

RNF138‐Mediated Ubiquitination and Degradation of NS5 Restricts Tick‐Borne Encephalitis Virus Infection

Advanced Science, EarlyView.
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun, Weijing Yang, Hao Zhou, Shuai Li, Xin Jiang, Jianyang Gu, Wenyan Zhang   +6 more
wiley   +1 more source

Clinical and Translational Radiation Oncology, a new player among the radiation oncology journals

Clinical and Translational Radiation Oncology, 2016
Pierre Blanchard
doaj   +1 more source

All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species

Advanced Science, EarlyView.
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao, Abulaihaiti Tuergong, Hanshu Yang, Shuang Xue, An Yan, Mingzhen Wang, Weilong Song, Wenzhe Si, Ruixue Wang   +8 more
wiley   +1 more source

Dosimetric Impact and Correction of Lipiodol Deposition on Photon-Beam Radiotherapy for Hepatocellular Carcinoma Using a Novel Simulation Model

Journal of Hepatocellular Carcinoma
Chenlei Guo,1,* Mengyuan Li,1,* Yirui Zhai,1,* Wei Sun,2,* Xiaowu Zhang,2,* Dong Yan,2,* Wei Zhang,1 Ying Cao,1 Zhen Wang,1 Kaixuan Zhang,1 Xin Feng,1 Shulian Wang,1 Yuan Tang,1 Ye-Xiong Li,1 Kuo Men,1 Bo ...
Guo C, Li M, Zhai Y, Sun W, Zhang X, Yan D, Zhang W, Cao Y, Wang Z, Zhang K, Feng X, Wang S, Tang Y, Li YX, Men K, Chen B   +15 more
doaj  

Radiation Oncology

Sarcoma, 2001
openaire   +2 more sources

Antigen Spreading via Localized Administration Enhances Adoptive TCR‐T Cell Therapy in Pancreatic Cancer

Advanced Science, EarlyView.
Cancer vaccines face limitations in pancreatic cancer due to insufficient tumor antigens. This ionic liquid ILvax via local tumor delivery triggers robust cDC1‐dependent systemic anti‐tumor immunity. It boosts endogenous CD8+ T cells and optimizes adoptive TCR‐T function, providing a promising synergistic therapeutic strategy.
Junming Huang, Qin Wang, Zhuo Yao, Qing Wang, Yongtao Ji, Minqi Yang, Meng Wang, Shiyi Shao, Xinyu Zhao, Fu Zhang, Tingbo Liang, Qida Hu   +11 more
wiley   +1 more source

Inhibition of KDEL Receptors Remodels the Tumor Microenvironment for T Cell Independent Tumor Regression

Advanced Science, EarlyView.
Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak, Hong Wang, Belinda Willard, Timothy A. Chan, William C Merrick, Zheng‐Rong Lu, Boaz Tirosh   +6 more
wiley   +1 more source

Association of Naples Prognostic Score with Survival in Patients with Inoperable Esophageal Squamous Cell Carcinoma Undergoing Chemoradiotherapy Combined with Immunotherapy

Journal of Inflammation Research
Xinyue Wei,* Dong Guo,* Yuanyuan Cai, Yang Li, Xiaoxiao Wang, Bingyi Zhang, Jianwen Li, Furong Hao Department of Radiation Oncology, Weifang People’s Hospital, Shandong Second Medical University, Weifang City, People’s Republic of China ...
Wei X, Guo D, Cai Y, Li Y, Wang X, Zhang B, Li J, Hao F   +7 more
doaj  

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

Advanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu, Shutao Zhang, Yumin Lin, Juyang Jiao, Zhiwei Fu, Qimin Hong, Ziyi Zhao, Xinhua Qu, Fei Su, Bing Yue   +9 more
wiley   +1 more source

Colorectal cancer radiotherapy utilization rate in a low-middle income country – a multicenter study in Indonesia

Contemporary Oncology
Vito Filbert Jayalie, Gregorius Ben Prajogi, Tiara Bunga Mayang Permata, Handoko ., Soehartati Gondhowiardjo, Indonesian Radiation Oncology Society*   +5 more
doaj   +1 more source