Results 101 to 110 of about 364,834 (265)
Meng Tian,1,2,* Minghui Zhao,2,* Linhong Jiang,2,* Jia Liu,2,* Gefenqiang Shen,2 Zhaoyue Zhang,2,3 Caiqiang Zhu,1 Sheng Zhang,2 Xinchen Sun,2 Yujing Shi,1 Xiaoke Di1,2 1Department of Oncology, Jurong Hospital Affiliated to
Tian M +10 more
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The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi +8 more
wiley +1 more source
Clinical and Translational Radiation Oncology, a new player among the radiation oncology journals
Pierre Blanchard
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This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He +10 more
wiley +1 more source
Chenlei Guo,1,* Mengyuan Li,1,* Yirui Zhai,1,* Wei Sun,2,* Xiaowu Zhang,2,* Dong Yan,2,* Wei Zhang,1 Ying Cao,1 Zhen Wang,1 Kaixuan Zhang,1 Xin Feng,1 Shulian Wang,1 Yuan Tang,1 Ye-Xiong Li,1 Kuo Men,1 Bo ...
Guo C +15 more
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RBM10 deficiency promotes anti‐PD‐1 resistance in lung adenocarcinoma by altering STING alternative splicing, which enhances CCL7 secretion and CCR2‐dependent M2 macrophage polarization. A positive feedback loop via mitochondrial transfer sustains this immunosuppression.
Weitong Gao +14 more
wiley +1 more source
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang +11 more
wiley +1 more source
Xinyue Wei,* Dong Guo,* Yuanyuan Cai, Yang Li, Xiaoxiao Wang, Bingyi Zhang, Jianwen Li, Furong Hao Department of Radiation Oncology, Weifang People’s Hospital, Shandong Second Medical University, Weifang City, People’s Republic of China ...
Wei X +7 more
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