Results 101 to 110 of about 364,834 (265)

Safety and Efficacy of Serplulimab Combined with Neoadjuvant Chemoradiotherapy in High-Risk Locally Advanced Rectal Cancer: A Retrospective Study

open access: yesCancer Management and Research
Meng Tian,1,2,* Minghui Zhao,2,* Linhong Jiang,2,* Jia Liu,2,* Gefenqiang Shen,2 Zhaoyue Zhang,2,3 Caiqiang Zhu,1 Sheng Zhang,2 Xinchen Sun,2 Yujing Shi,1 Xiaoke Di1,2 1Department of Oncology, Jurong Hospital Affiliated to
Tian M   +10 more
doaj  

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

open access: yesAdvanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi   +8 more
wiley   +1 more source

Clinical and Translational Radiation Oncology, a new player among the radiation oncology journals

open access: yesClinical and Translational Radiation Oncology, 2016
Pierre Blanchard
doaj   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

open access: yesAdvanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He   +10 more
wiley   +1 more source

Dosimetric Impact and Correction of Lipiodol Deposition on Photon-Beam Radiotherapy for Hepatocellular Carcinoma Using a Novel Simulation Model

open access: yesJournal of Hepatocellular Carcinoma
Chenlei Guo,1,* Mengyuan Li,1,* Yirui Zhai,1,* Wei Sun,2,* Xiaowu Zhang,2,* Dong Yan,2,* Wei Zhang,1 Ying Cao,1 Zhen Wang,1 Kaixuan Zhang,1 Xin Feng,1 Shulian Wang,1 Yuan Tang,1 Ye-Xiong Li,1 Kuo Men,1 Bo ...
Guo C   +15 more
doaj  

RBM10 Deficiency Promotes Anti‐PD‐1 Resistance in LUAD via STING Alternative Splicing‐Driven CCL7 Signaling and Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
RBM10 deficiency promotes anti‐PD‐1 resistance in lung adenocarcinoma by altering STING alternative splicing, which enhances CCL7 secretion and CCR2‐dependent M2 macrophage polarization. A positive feedback loop via mitochondrial transfer sustains this immunosuppression.
Weitong Gao   +14 more
wiley   +1 more source

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang   +11 more
wiley   +1 more source

Colorectal cancer radiotherapy utilization rate in a low-middle income country – a multicenter study in Indonesia

open access: yesContemporary Oncology
Vito Filbert Jayalie   +5 more
doaj   +1 more source

Association of Naples Prognostic Score with Survival in Patients with Inoperable Esophageal Squamous Cell Carcinoma Undergoing Chemoradiotherapy Combined with Immunotherapy

open access: yesJournal of Inflammation Research
Xinyue Wei,* Dong Guo,* Yuanyuan Cai, Yang Li, Xiaoxiao Wang, Bingyi Zhang, Jianwen Li, Furong Hao Department of Radiation Oncology, Weifang People’s Hospital, Shandong Second Medical University, Weifang City, People’s Republic of China ...
Wei X   +7 more
doaj  

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