Results 111 to 120 of about 364,834 (265)

Radiotherapy Enhances the Oncolytic Efficacy of the Novel Oncolytic Herpesvirus VG161 and Amplifies Its Antitumor Immunity in Breast Cancer

Advanced Science, EarlyView.
RT promotes VG161 replication in BC and its immunostimulatory transgenes expression, which is mediated by the upregulation of GADD34 and HVEM caused by RT. The combination therapy with VG161 and RT increases the abundances of tumor‐infiltrating lymphocytes and elicits potent systemic antitumor immunity, thereby effectively inhibiting local tumors and ...
Lijuan Lyu, Ming Yi, Ji Chen, Zeda Zhao, Ruocen Liao, Yingnan Wang, Shengtao Hu, Jun Ding, Ronghua Zhao, William Jia, Yinan Shen, Yongchang Wei, Kongming Wu, Zhijun Dai   +13 more
wiley   +1 more source

Artificial Intelligence in Image Assisted Radiation Oncology. [PDF]

Cancers (Basel)
Wang H, Zhao Y, Chen X, McDonald B, Li Y, Xie J, Rhee DJ, Lim TY, Netherton TJ, Phan J, Spiotto MT, Lin MH.   +11 more
europepmc   +1 more source

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

Advanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li, Ka Man Ng, Xingsheng Shu, Xiaoxue Chai, Kai Yau Wong, Gopesh Srivastava, Anthony T.C. Chan, Wai Yee Chan, Qian Tao   +8 more
wiley   +1 more source

Editorial: Importance of quality assurance in radiation oncology clinical trials. [PDF]

Front Oncol
FitzGerald TJ, Laurie F, Iandoli M, Smith K, Bishop-Jodoin M.   +4 more
europepmc   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Effectiveness and Safety of Anlotinib with or without PD-1 Blockades in Patients with Platinum-Resistant or Immunotherapy-Resistant Recurrent/Metastatic Nasopharyngeal Carcinoma: A Retrospective, Real-World Study

Drug Design, Development and Therapy
Kailin Chen,1 Yuyi Li,12 Xiaoyu Chen,12 Weichang Zhu,12 Yuchen Shi,12 Xu Ye,1 Cuihong Jiang,1 Yajun Li,3 Feng Liu,11Department of Radiation Oncology, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer ...
Chen K, Li Y, Chen X, Zhu W, Shi Y, Ye X, Jiang C, Li Y, Liu F   +8 more
doaj  

Large language models for scalable standardization in radiation oncology. [PDF]

Phys Imaging Radiat Oncol
Floyd W, Wahid KA, Anderson B, Knäusl B, Moreno AC.   +4 more
europepmc   +1 more source

mTORC2 Phosphorylation of GSDME‐N Drives Cullin4B‐Mediated Proteasomal Degradation to Suppress Pyroptosis and Confer Radioresistance in Small Cell Lung Cancer

Advanced Science, EarlyView.
Radioresistance severely limits the efficacy of therapies for small cell lung cancer (SCLC). This study reveals a novel mechanism of resistance driven by the active suppression of pyroptosis. Specifically, the mTORC2 complex directly phosphorylates GSDME‐N and promotes its CUL4B‐mediated ubiquitination and proteasomal degradation.
Qing‐qing Xu, Ci‐ming Sun, Sui‐xian Zhang, Rui Li, Chen‐fei Wu, Zai‐shan Lin, Li Li, Run‐zhe Chen, Qi‐wen Li, Yuan‐yuan Chen, Xuan Li, Ming Chen   +11 more
wiley   +1 more source

Radiation Oncology [PDF]

, 2020
Jessica W. Lee, David G. Kirsch
openaire   +2 more sources

A Retrospective Evaluation of Setup Errors Associated with Respiratory Motion Management Techniques in Stereotactic Body Radiation Therapy for Hepatic Malignancies

Journal of Hepatocellular Carcinoma
Ji-Hua Han,* Dong-Cheng He,* Xiao-Ye Zhang, Yan Zhang, Jun Hong, Ting-Ting Shi, Zhi-Jian Zhu Department of Radiation Oncology, The Affiliated Huaian No.1 People’s Hospital of Nanjing Medical University, Huai’an, Jiangsu Province, 223300 ...
Han JH, He DC, Zhang XY, Zhang Y, Hong J, Shi TT, Zhu ZJ   +6 more
doaj