Results 91 to 100 of about 363,464 (264)

Quantum Photothermal Self‐Monitoring Fiber Probes for In Vivo Photothermal Therapy

Advanced Science, EarlyView.
A miniaturized quantum photothermal fiber probe based on a metal/polymer/glass composite optoelectronic fiber that simultaneously guides lightwave and microwave was developed for the first time. The probe achieves enhanced photothermal conversion (13°C/mW, 25°C–120°C range) while providing real‐time self‐monitoring with 0.2°C thermal resolution at the ...
Wanjun Li, Ruixiao Hu, Jie Mao, Jin Wo, Yunsong Zhang, Liang Chen, Ying Liu, Zhibo Li, Yongxin Lin, Minghui Du, Yaofei Chen, Libing Zhou, Tuan Guo   +12 more
wiley   +1 more source

Optimizing Left-Sided Breast Cancer Radiotherapy: Strategy-Dependent Trade-Offs Among VMAT and Hybrid Techniques

Cancer Management and Research
Rocco Mottareale,1 Francesca Buonanno,1 Valentina d’Alesio,1 Sara Falivene,1 Marcello Serra,1 Cecilia Arrichiello,1 Gianluca Ametrano,1 Piera Ferraioli,1 Gaetano Gagliardo,2 Rossella Di Franco,1 Simona Mercogliano,1 Paolo Muto,2 Vincenzo Ravo1 ...
Mottareale R, Buonanno F, d'Alesio V, Falivene S, Serra M, Arrichiello C, Ametrano G, Ferraioli P, Gagliardo G, Di Franco R, Mercogliano S, Muto P, Ravo V   +12 more
doaj  

Effect of Serum Interleukin-6 Concentration on the Prognosis After Radiotherapy for Patients With Hepatocellular Carcinoma

Canadian Journal of Gastroenterology and Hepatology
Conclusions: The prognosis of HCC patients receiving RT was worse for those with a pre-RT serum IL-6 concentration > 7.8 pg/mL than those with a pre-RT serum IL-6 concentration ≤ 7.8 pg/mL.
Yong Hu, Yongkang Zhou, Shisuo Du, Wenchao Zhu, Yixing Chen, Zhaochong Zeng   +5 more
doaj   +1 more source

PancDS in Real‐World Practice: A Prospective Multicenter Validation of a Clinical Decision‐Support System Bridging Experience Gaps in Pancreatic Lesion Diagnosis

Advanced Science, EarlyView.
A biomimetic artificial intelligence system, PancDS, has been developed to distinguish pancreatic ductal adenocarcinoma from mass‐forming pancreatitis by adaptively integrating clinical data, radiomics, and deep learning features. Validated across multicenter, reader‐study, and prospective settings, PancDS improves diagnostic accuracy, particularly for
Zhibo Wang, Weinuo Qu, Wenwen Cai, Chuhuai Wang, Chenxi Lyu, Qingguo Xie, Qian Chu, Yaqi Shen, Peng Xiao, Feng Li, Qingpeng Zhang, Jiali Li, Jeong Min Lee, Zhen Li   +13 more
wiley   +1 more source

Radiation-Induced Liver Injury: An Overview

Journal of Hepatocellular Carcinoma
Jing Sun,1,* Hao-ran Lu,1,* Jian-hui Wu,2,* Dong Li,1,* Tao Zhang,1 Xue-zhang Duan1 1Department of Radiation Oncology, Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, Beijing, People’s ...
Sun J, Lu HR, Wu JH, Li D, Zhang T, Duan XZ   +5 more
doaj  

mTORC2 Phosphorylation of GSDME‐N Drives Cullin4B‐Mediated Proteasomal Degradation to Suppress Pyroptosis and Confer Radioresistance in Small Cell Lung Cancer

Advanced Science, EarlyView.
Radioresistance severely limits the efficacy of therapies for small cell lung cancer (SCLC). This study reveals a novel mechanism of resistance driven by the active suppression of pyroptosis. Specifically, the mTORC2 complex directly phosphorylates GSDME‐N and promotes its CUL4B‐mediated ubiquitination and proteasomal degradation.
Qing‐qing Xu, Ci‐ming Sun, Sui‐xian Zhang, Rui Li, Chen‐fei Wu, Zai‐shan Lin, Li Li, Run‐zhe Chen, Qi‐wen Li, Yuan‐yuan Chen, Xuan Li, Ming Chen   +11 more
wiley   +1 more source

Neoadjuvant Chemoimmunotherapy for the Treatment of Locally Advanced Nasopharyngeal Carcinoma in Non-Endemic Regions: A Single-Arm Phase 2 Clinical Trial

Cancer Management and Research
Lingran Zhou, Zhenchao Tao, Yan Zhou, Liping Yang, Yangyang Zhang, Jian He, Bin Sun, Ru Wang, Jing Yang, Jin Gao Department of Radiation Oncology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and ...
Zhou L, Tao Z, Zhou Y, Yang L, Zhang Y, He J, Sun B, Wang R, Yang J, Gao J   +9 more
doaj  

Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies

Advanced Science, EarlyView.
In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang, Xinxin Zou, Jiansong Zhou, Qinmiao Sun, Dahua Chen   +4 more
wiley   +1 more source

Safety and Efficacy of Serplulimab Combined with Neoadjuvant Chemoradiotherapy in High-Risk Locally Advanced Rectal Cancer: A Retrospective Study

Cancer Management and Research
Meng Tian,1,2,* Minghui Zhao,2,* Linhong Jiang,2,* Jia Liu,2,* Gefenqiang Shen,2 Zhaoyue Zhang,2,3 Caiqiang Zhu,1 Sheng Zhang,2 Xinchen Sun,2 Yujing Shi,1 Xiaoke Di1,2 1Department of Oncology, Jurong Hospital Affiliated to
Tian M, Zhao M, Jiang L, Liu J, Shen G, Zhang Z, Zhu C, Zhang S, Sun X, Shi Y, Di X   +10 more
doaj  

Guardians of Sensation: Evaluating Metformin’s Power Against Chemotherapy-Induced Neuropathy

International Journal of Breast Cancer
Conclusion: Metformin may modestly reduce the incidence of CIPN in patients receiving paclitaxel chemotherapy, although the observed effect was not statistically significant.
Hamid Nasrolahi, Ahmad Mosalaei, Susan Andalibi, Shapour Omidvari, Mansour Ansari, Mohammad Mohammadianpanah, Niloofar Ahmadloo, Samineh Sadeghian, Afshin Karimzadeh, Ehsan Mohammad Hosseini   +9 more
doaj   +1 more source