Results 81 to 90 of about 560,406 (374)

Advances in the management of HPV-related oropharyngeal cancer [PDF]

open access: yes, 2019
Patients with human papillomavirus- (HPV-) related oropharyngeal squamous cell carcinoma (OPSCC) have a better prognosis than HPV-negative OPSCC when treated with standard high-dose cisplatin-based chemoradiotherapy.
Brugnoletti, O.   +6 more
core   +1 more source

Advances and future of Radiation Oncology [PDF]

open access: yesReports of Practical Oncology & Radiotherapy, 2013
Review of recent advances and vision for future developments in clinical practice of Radiation Oncology.There have been substantial research and technological developments in Radiation Oncology over the past 40 years.The relevant literature was reviewed and the authors offer their perspective on future opportunities for advancement in Radiation ...
Sasa Mutic, Carlos A. Perez
openaire   +3 more sources

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

DATA SCIENCE METHODS FOR STANDARDIZATION, SAFETY, AND QUALITY ASSURANCE IN RADIATION ONCOLOGY [PDF]

open access: yes, 2020
Radiation oncology is the field of medicine that deals with treating cancer patients through ionizing radiation. The clinical modality or technique used to treat the cancer patients in the radiation oncology domain is referred to as radiation therapy ...
Syed, Khajamoinuddin
core   +1 more source

The role of PDGF in radiation oncology [PDF]

open access: yesRadiation Oncology, 2007
AbstractPlatelet-derived growth factor (PDGF) was originally identified as a constituent of blood serum and subsequently purified from human platelets. PDGF ligand is a dimeric molecule consisting of two disulfide-bonded chains from A-, B-, C- and D-polypeptide chains, which combine to homo- and heterodimers.
Minglun Li   +2 more
openaire   +4 more sources

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

open access: yesMolecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau   +9 more
wiley   +1 more source

WeWhoCurie: An Initiative to Advocate for Those Underrepresented in Radiation Oncology

open access: yesAdvances in Radiation Oncology, 2023
Purpose: An initiative to advocate for those underrepresented in radiation oncology. Methods and Materials: Inspired by the success of the #ILookLikeAnEngineer and #ILookLikeASurgeon campaigns, this initiative aimed to break down stereotypes in ...
Joy Ogunmuyiwa, MD, MPH   +9 more
doaj  

ASTRO Journals' Data Sharing Policy and Recommended Best Practices. [PDF]

open access: yes, 2019
Transparency, openness, and reproducibility are important characteristics in scientific publishing. Although many researchers embrace these characteristics, data sharing has yet to become common practice.
Braverman, Lisa   +8 more
core   +2 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

First South African Congress of Oncology 2019

open access: yesSouth African Journal of Oncology, 2019
This conference report encompasses abstracts and posters presented at the First South African Congress of Oncology on ‘Transporting Cancer Care into 2020 and Beyond’, 08–11 August 2019, at Cape Town International Convention Centre, Cape Town, South ...
Raymond P. Abratt
doaj   +1 more source

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