Results 91 to 100 of about 1,103,532 (303)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Flight test of a pure-tone acoustic source [PDF]

open access: yes
Static and flight testing of a pure-tone acoustic source were conducted in order to: (1) determine if a 4-KHz tone radiated by a source in flight and mixed with broadband aircraft flyover noise could be measured on the ground with a high degree of ...
Mueller, A. W., Preisser, J. S.
core   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

STEERABLE TOROIDAL BIFOCAL LENS-ARRAY ANTENNA IN 57–64 GHZ RANGE

open access: yesИзвестия высших учебных заведений России: Радиоэлектроника, 2019
Introduction. Currently, one of the most promising approaches to the development of 5th generation mobile wireless systems is the deployment of heterogeneous networks based on existing LTE cellular systems having both large and small cells.
Alexander A. Maltsev   +3 more
doaj   +1 more source

Multimodal far-field acoustic radiation pattern: An approximate equation [PDF]

open access: yes
The far-field sound radiation theory for a circular duct was studied for both single mode and multimodal inputs. The investigation was intended to develop a method to determine the acoustic power produced by turbofans as a function of mode cut-off ratio.
Rice, E. J.
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

MODELING THE CONTROLLABILITY OF CHARACTERISTICS OF PLASMON GRAPHENE NANOANTENNA GRATINGS IN THE MID-IR RANGE

open access: yesНадежность и качество сложных систем
Background. The introduction of nanoantennas for optical wireless communications in the infrared (IR) and visible bands enables higher data rates while reducing antenna size.
G.S. Makeeva
doaj   +1 more source

Most desirable terrain, e.g., flat vs valley location, part 5.1B [PDF]

open access: yes
Ground reflections which are similar for all (Yagi) elements of a phased array and change the radiation pattern of the single elements are discussed. This consequently yields a change of the radiation pattern of the entire array.
Rottger, J.
core   +1 more source

Home - About - Disclaimer - Privacy