Results 41 to 50 of about 3,742,396 (307)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Hesperidin as a natural Radio-Protector [PDF]

Journal of Advanced Biomedical Sciences, 2015
Despite widespread usage of ionizing radiation in medical diagnosis and treatment methods, development of radio-protective agents is important in modulating normal tissue damages.
Zhila Ghorbani, Gholamhassan Haddadi, Reza Fardid   +2 more
doaj  

Polar microalgae extracts protect human HaCaT keratinocytes from damaging stimuli and ameliorate psoriatic skin inflammation in mice

Biological Research, 2023
Background Polar microalgae contain unique compounds that enable them to adapt to extreme environments. As the skin barrier is our first line of defense against external threats, polar microalgae extracts may possess restorative properties for damaged ...
YoonHee Lim, So-Hyun Park, Eun Jae Kim, HeeJun Lim, Jinsun Jang, In-Sun Hong, Sanghee Kim, YunJae Jung   +7 more
doaj   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

"Adaptive response" - some underlying mechanisms and open questions [PDF]

, 2008
Organisms are affected by different DNA damaging agents naturally present in the environment or released as a result of human activity. Many defense mechanisms have evolved in organisms to minimize genotoxic damage. One of them is induced radioresistance
Stephka G. Chankova, Dimova, Evgeniya G, Chankova, Stephka G, Peter E. Bryant, Bryant, Peter Edward, Evgeniya G. Dimova   +5 more
core   +1 more source

Research on the mechanisms of natural products in radiation protection

Frontiers in Bioengineering and Biotechnology
Radiation exposure initiates a cascade of reactions, including the release of reactive oxygen species, DNA double-strand breaks, and cellular apoptosis, leading to cell death, tissue damage, and potentially the development of cancer.
Xiaoxue Li, Luyao Yu, Hongchi Xu, Xiaowen Xing, Wenhui Wu, Yifei Feng, Li Ma, Zheng Zhou, Bailin Li, Ying He   +9 more
doaj   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Gene Expression Profiles in Radiation Workers Occupationally Exposed to Ionizing Radiation

, 2009
Ionizing radiation OR) imposes risks to human health and the environment. IR at low doses and low (lose rates has the potency to initiate carcinogenesis.
GHILARDI-NETTO, Thomaz, MELLO, Stephano Spano, PASSOS, Geraldo Aleixo da Silva, SANDRIN-GARCIA, Paula, DONADI, Eduardo Antonio, SAKAMOTO-HOJO, Elza Tiemi, JUNTA, Cristina Moraes, FACHIN, Ana Lucia   +7 more
core   +1 more source

Bone protective agents in children [PDF]

, 2017
Evaluation of bone health in childhood is important to identify children who have inadequate bone mineralisation and who may benefit from interventions to decrease their risk of osteoporosis and subsequent fracture.
Ahmed, S Faisal, S Faisal Ahmed, Ahmed, S. Faisal, Wood, Claire Louise, Claire Louise Wood   +4 more
core   +1 more source