Results 11 to 20 of about 32,925 (248)

OGG1 competitive inhibitors show important off-target effects by directly inhibiting efflux pumps and disturbing mitotic progression

Frontiers in Cell and Developmental Biology, 2023
One of the most abundant DNA lesions induced by Reactive oxygen species (ROS) is 8-oxoG, a highly mutagenic lesion that compromises genetic instability when not efficiently repaired.
Xhaferr Tanushi, Xhaferr Tanushi, Guillaume Pinna, Guillaume Pinna, Marie Vandamme, Marie Vandamme, Capucine Siberchicot, Capucine Siberchicot, Ostiane D’Augustin, Ostiane D’Augustin, Ostiane D’Augustin, Anne-Marie Di Guilmi, Anne-Marie Di Guilmi, J. Pablo Radicella, J. Pablo Radicella, Bertrand Castaing, Rebecca Smith, Sebastien Huet, Sebastien Huet, François Leteurtre, François Leteurtre, Anna Campalans, Anna Campalans   +22 more
doaj   +1 more source

XLF/Cernunnos loss impairs mouse brain development by altering symmetric proliferative divisions of neural progenitors

Cell Reports, 2023
Summary: XLF/Cernunnos is a component of the ligation complex used in classical non-homologous end-joining (cNHEJ), a major DNA double-strand break (DSB) repair pathway.
Amandine Bery, Olivier Etienne, Laura Mouton, Sofiane Mokrani, Christine Granotier-Beckers, Laurent R. Gauthier, Justyne Feat-Vetel, Thierry Kortulewski, Elodie A. Pérès, Chantal Desmaze, Philippe Lestaveal, Vilma Barroca, Antony Laugeray, Fawzi Boumezbeur, Vincent Abramovski, Stéphane Mortaud, Arnaud Menuet, Denis Le Bihan, Jean-Pierre de Villartay, François D. Boussin   +19 more
doaj   +1 more source

Rapid detection of argan oil adulteration by frying oils using laser induced fluorescence spectroscopy combined with chemometrics tools

Grasas y Aceites, 2023
There is a contentious need for robust and rapid methodologies for maintaining the authenticity of foods. The aim of this study was to detect and quantify argan oil adulteration using Laser Induced Fluorescence (LIF) spectroscopy coupled with ...
S. Farres, L. Srata, M. Chikri, S. Addou, F. Fethi   +4 more
doaj   +1 more source

Validation of DRAGON4/DONJON4 simulation methodology for a typical MNSR by calculating reactivity feedback coefficient and neutron flux

Results in Physics, 2018
The MNSR is a pool type research reactor, which is difficult to model because of the importance of neutron leakage. The aim of this study is to evaluate a 2-D transport model for the reactor compatible with the latest release of the DRAGON code and 3-D ...
Jamal Al Zain, O. El Hajjaji, T. El Bardouni, H. Boukhal, Otman Jaï   +4 more
doaj   +1 more source

Influence of cellular models and individual factor in the biological response to chest CT scan exams

European Radiology Experimental, 2022
Background While computed tomography (CT) exams are the major cause of medical exposure to ionising radiation, there is increasing evidence that the potential radiation-induced risks must be documented.
Clément Devic, Larry Bodgi, Laurène Sonzogni, Frank Pilleul, Hervé Ribot, Charlotte De Charry, François Le Moigne, Didier Paul, Fanny Carbillet, Mélodie Munier, Nicolas Foray   +10 more
doaj   +1 more source

Radiation sterilization [PDF]

Journal of Clinical Pathology, 1961
The sterilization by radiation of disposable medical items has been investigated. Various vegetative and spore-bearing bacteria have been irradiated and results indicate that 2·5 Mrad can be recommended to give a high degree of sterility. Spores of B. pumilus (E.601) showed such resistance that it might be a suitable test organism for determining the ...
E M, DARMADY, K E, HUGHES, M M, BURT, B M, FREEMAN, D B, POWELL   +4 more
openaire   +2 more sources

An overview of last decade’s developments in RayXpert®, a 3D Monte Carlo code

EPJ Nuclear Sciences & Technologies
This article provides an overview of the developments made over the last 10 years within RayXpert®, a CAD-based geometry 3D Monte Carlo software developed by TRAD – Tests & Radiations.
Dray Nicolas, Mary Nicolas, Dossat Cédric, Bourgoin Jefferson, Chatry Nathalie   +4 more
doaj   +1 more source

Influence of cellular models and individual factor in the biological response to head CT scan exams

European Radiology Experimental, 2022
Background While computed tomography (CT) exams are the major cause of medical exposure to ionising radiation, the radiation-induced risks must be documented. We investigated the impact of the cellular models and individual factor on the deoxyribonucleic
Clément Devic, Larry Bodgi, Laurène Sonzogni, Frank Pilleul, Hervé Ribot, Charlotte De Charry, François Le Moigne, Didier Paul, Fanny Carbillet, Mélodie Munier, Nicolas Foray   +10 more
doaj   +1 more source

The netrin-1 receptor UNC5C contributes to the homeostasis of undifferentiated spermatogonia in adult mice

Stem Cell Research, 2022
In adult testis, the cell mobility is essential for spermatogonia differentiation and is suspected to regulate spermatogonial stem cell fate. Netrin-1 controls cell migration and/or survival according to the cellular context. Its involvement in some self-
Vilma Barroca, Chrystele Racine, Laurent Pays, Pierre Fouchet, Mathieu Coureuil, Isabelle Allemand   +5 more
doaj   +1 more source

Low altitude energetic electron lifetimes after enhanced magnetic activity as deduced from SAC-C and DEMETER data [PDF]

Annales Geophysicae, 2010
When flux enhancements of energetic electrons are produced as a consequence of geomagnetic storm occurrence, they tend to vanish gradually when the magnetic activity calms down and the fluxes decay to quiet-time levels.
S. Benck, L. Mazzino, M. Cyamukungu, J. Cabrera, V. Pierrard, V. Pierrard   +5 more
doaj   +1 more source