Results 31 to 40 of about 33,535 (269)

Radiation Protection at Synchrotron Radiation Facilities [PDF]

open access: yesRadiation Protection Dosimetry, 2001
A synchrotron radiation (SR) facility typically consists of an injector, a storage ring, and SR beamlines. The latter two features are unique to SR facilities, when compared to other types of accelerator facilities. The SR facilities have the characteristics of low injection beam power, but high stored beam power.
J C, Liu, V, Vylet
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Cosmological constraints on $$f(Q)$$ f ( Q ) gravity with redshift space distortion data

open access: yesEuropean Physical Journal C: Particles and Fields
In this paper, we explore one of Einstein’s alternative formulations which involves the non-metricity scalar, Q, within the framework of f(Q) theory. Our study focuses on solving the modified Friedmann equations for the case of dust matter, $$\rho =\rho ...
Dalale Mhamdi   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Dose metrology: TLD/OSL dose accuracy and energy response performance

open access: yesNuclear Engineering and Technology, 2023
An essential step in evaluating and comparing the performance of two passive radiation dosimeter types, thermosluminescent (TLD) and optically stimulated luminescence (OSL), used by workers in environments with ionizing radiation for individual ...
Omaima Essaad Belhaj   +9 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Testing Running Vacuum Energy in f(Q) Gravity with DESI Data

open access: yesUniverse
In this paper, we investigate the running vacuum energy (RVE) model within the framework of f(Q) gravity (f(Q)-RVE). In this context, the modified Friedmann equation can be used to establish a formal analogy with the structure of the RVE.
Dalale Mhamdi   +3 more
doaj   +1 more source

Syndecan-1 Stimulates Adult Neurogenesis in the Mouse Ventricular-Subventricular Zone after Injury

open access: yesiScience, 2020
Summary: The production of neurons from neural stem cells (NSCs) persists throughout life in the mouse ventricular-subventricular zone (V-SVZ). We have previously reported that NSCs from adult V-SVZ are contained in cell populations expressing the ...
Marc-André Mouthon   +5 more
doaj   +1 more source

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