Results 71 to 80 of about 2,431 (219)

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Dynamics of femtosecond lasers and induced plasma in non-Kerr nonlinear transparent materials: Competing effects of electron–hole radiative recombinations and single-electron diffusions

AIP Advances
Modern laser micromachining utilizes ultrashort optical fields, such as femtosecond lasers, to perform high-precision processings on solid materials, including cutting, drilling, ablation, polishing, and scripturing.
I. Ngek Ndifon, Alain M. Dikandé
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Ionized Envelopes Around Protoplanets and the Role of Radiative Feedback in Gas Accretion

The Astrophysical Journal
Planetary growth within protoplanetary disks involves the accreting of material from their surroundings, yet the underlying mechanisms and physical conditions of the accreting gas remain debated.
Matías Montesinos, Juan Garrido-Deutelmoser, Jorge Cuadra, Mario Sucerquia, Nicolás Cuello, Matthias R. Schreiber, María Paula Ronco, Octavio M. Guilera   +7 more
doaj   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Rubo Xing, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +16 more
wiley   +1 more source

First measurement of proton's charge form factor at very low Q2 with initial state radiation

Physics Letters B, 2017
We report on a new experimental method based on initial-state radiation (ISR) in e–p scattering, which exploits the radiative tail of the elastic peak to study the properties of electromagnetic processes and to extract the proton charge form factor (GEp)
M. Mihovilovič, A.B. Weber, P. Achenbach, T. Beranek, J. Beričič, J.C. Bernauer, R. Böhm, D. Bosnar, M. Cardinali, L. Correa, L. Debenjak, A. Denig, M.O. Distler, A. Esser, M.I. Ferretti Bondy, H. Fonvieille, J.M. Friedrich, I. Friščić, K. Griffioen, M. Hoek, S. Kegel, Y. Kohl, H. Merkel, D.G. Middleton, U. Müller, L. Nungesser, J. Pochodzalla, M. Rohrbeck, S. Sánchez Majos, B.S. Schlimme, M. Schoth, F. Schulz, C. Sfienti, S. Širca, S. Štajner, M. Thiel, A. Tyukin, M. Vanderhaeghen, M. Weinriefer   +38 more
doaj   +1 more source

Buffering of Aerosol‐Cloud Adjustments by Coupling Between Radiative Susceptibility and Precipitation Efficiency

Geophysical Research Letters
Aerosol‐cloud interactions (ACI) in warm clouds are the primary source of uncertainty in effective radiative forcing (ERF) during the historical period and, by extension, inferred climate sensitivity.
Ci Song, Daniel T. McCoy, Trude Eidhammer, Andrew Gettelman, Isabel L. McCoy, Duncan Watson‐Parris, Casey J. Wall, Gregory Elsaesser, Robert Wood   +8 more
doaj   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Blue Luminescence from N-doped Graphene

The Astrophysical Journal
Blue luminescence (BL) has been observed in various astrophysical environments, such as the inner region of the Red Rectangle Nebula. It has been previously linked to small polycyclic aromatic hydrocarbons.
Shu-Yu Lin, Sheng-Lung Chou, Tzu-Ping Huang, Meng-Yeh Lin, Hui-Fen Chen, Peter J. Sarre, Chien-Ming Tseng, Yu-Jong Wu   +7 more
doaj   +1 more source