Results 81 to 90 of about 26,075,196 (289)

Aerosol modeling over Europe: 2. Interannual variability of aerosol shortwave direct radiative forcing [PDF]

, 2007
Aerosol distribution over Europe and its direct radiative forcing have been simulated with a regional atmosphere-chemistry model and an off-line radiation transfer model. Primary and secondary organic and inorganic aerosols have been considered.
Hungershöfer, K., Marmer, Elina, Langmann, B., Hungershöfer, Katja, Langmann, Bärbel, Trautmann, Thomas, Trautmann, T., Marmer, E.   +7 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Collisional and Radiative Processes in Optically Thin Plasmas [PDF]

, 2013
Most of our knowledge of the physical processes in distant plasmas is obtained through measurement of the radiation they produce. Here we provide an overview of the main collisional and radiative processes and examples of diagnostics relevant to the ...
S. Bradshaw, J. Raymond
semanticscholar   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Future estimates of tropospheric ozone radiative forcing and methane turnover - the impact of climate change [PDF]

, 2000
We present a range of estimates for future radiative forcings due to changes in tropospheric ozone (O3T). Ozone distributions were generated by the UKMO 3-D chemistry-transport model for 1990, 2030, 2060, and 2100, using four sets of boundary conditions.
Collins, W. J., Stevenson, D. S.; id_orcid, Derwent, R. G., Johnson, C. E., Edwards, J. M.   +4 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Screw dislocation-induced growth spirals as emissive exciton localization centers in Al-rich AlGaN/AlN quantum wells

AIP Advances, 2015
Screw dislocations in Al-rich AlGaN/AlN quantum wells cause growth spirals with an enhanced Ga incorporation, which create potential minima. Although screw dislocations and their surrounding potential minima suggest non-radiative recombination processes ...
Mitsuru Funato, Ryan G. Banal, Yoichi Kawakami   +2 more
doaj   +1 more source

The Influence of Neighbouring Clouds on the Clear Sky Reflectance Studied with the 3-D Transport Code RADUGA [PDF]

, 2005
Operational remote sensing of terrestrial atmosphere is heavily based on the 1-D radiative transfer equation. However, cloudy scenes are influenced by 3-D effects (e.g., illumination from cloud sides, etc.).
Nikolaeva, O.V., Kuznetsov, V.S., Germogenova, T.A., Kokhanovsky, A.A., Bass, L.P., Mayer, B.   +5 more
core   +1 more source