Results 51 to 60 of about 94,314 (315)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Numerical Simulation and Experimental Study on Chip Radiator with Enhanced Heat Transfer Structure
Zhileng xuebao, 2015 The heat dissipation of super or large computer server CPU has become the bottleneck for the development of high performance computer, therefore the cooling of super or large computer server attracted more and more attention.
Zhu Kai +4 more
doaj +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Capillary radiator Patent [PDF]
, 1970 Capillary radiator for carrying heat transfer liquid in planetary spacecraft ...
Vary, A.
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Experimental Study of Heat Transfer Enhancement in Car Radiator by Using copper and aluminum Nanofluids [PDF]
Engineering and Technology Journal, 2015 The cooling system of a car plays an important role in vehicle's performance, consists of two main parts, known as radiator and fan. Improving thermal efficiency of engine leads to increase the engine's performance, decline the fuel consumption and ...
Khalid Faisal Sultan +2 more
doaj +1 more source
Hadron Blind Detector for the PHENIX Experiment at RHIC [PDF]
, 2006 The PHENIX collaboration has designed a conceptually new Hadron Blind Detector (HBD) for electron identification in high density hadron environment. The HBD will identify low momentum electron-positron pairs to reduce the combinatorial background in the ...
A. Milov, null null
core +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A novel type of proximity focusing RICH counter with multiple refractive index aerogel radiator
, 2005 A proximity focusing ring imaging Cherenkov detector, with the radiator consisting of two or more aerogel layers of different refractive indices, has been tested in 1-4 GeV/c pion beams at KEK.
A. Gorišek +24 more
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source