Results 31 to 40 of about 1,460,787 (297)

O-GlcNAc regulation of autophagy and α-synuclein homeostasis; implications for Parkinson’s disease

open access: yesMolecular Brain, 2017
Post-translational modification on protein Ser/Thr residues by O-linked attachment of ß-N-acetyl-glucosamine (O-GlcNAcylation) is a key mechanism integrating redox signaling, metabolism and stress responses.
Willayat Y. Wani   +8 more
doaj   +1 more source

Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease

open access: yesRedox Biology, 2014
Oxidative stress including DNA damage, increased lipid and protein oxidation, are important features of aging and neurodegeneration suggesting that endogenous antioxidant protective pathways are inadequate or overwhelmed.
Samantha Giordano   +2 more
doaj   +1 more source

Green synthetic methodologies for radical generation [PDF]

open access: yes, 2022
openThe use of radicals as intermediates in total synthesis has evolved since their initial use in the latter half of the twentieth century. Radical generation from metal hydride methodologies has shifted to “greener” techniques including catalytic metal-
CATALDI, FRANCESCO
core  

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld   +5 more
wiley   +1 more source

Little Free Libraries: A View from the Back Road [PDF]

open access: yes, 2017
Commentary piece in response to Schmidt, H. and Hale, J. (2017). Little Free Libraries®: Interrogating the impact of the branded book exchange.
Olson Beal, Heather K., Burrow, Lauren
core   +1 more source

Role of mitochondrial dysfunction and dysregulation of Ca2+ homeostasis in the pathophysiology of insulin resistance and type 2 diabetes

open access: yesJournal of Biomedical Science, 2017
Metabolic diseases such as obesity, type 2 diabetes (T2D) and insulin resistance have attracted great attention from biomedical researchers and clinicians because of the astonishing increase in its prevalence.
Chih-Hao Wang, Yau-Huei Wei
doaj   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo   +9 more
wiley   +1 more source

Erratum to: Stewart, N. and Bigirindavyi, M. (2025). Conversational Reflection on the Co-Creation of the Principal Preparation Answerability Rubric (PPAR). Radical Teacher, 131, pp. 49-57.

open access: yesRadical Teacher
This erratum addresses an error in the original article’s abstract, which included a sentence from a previous, anonymized version of the submission. The phrase “[University Name]" was removed from the abstract in the following sentence: "The Principal ...
Radical Teacher Editorial Team
doaj   +1 more source

En un lugar de la Mancha... : discurso pronunciado en la velada que se celebró en el Casino Republicano Radical la noche del 7 de mayo de 1905 con motivo del centenario del "Quijote" [PDF]

open access: yes, 1905
Discurso pronunciado en la velada celebrada en el Casino Republicano Radical, el 7 de mayo de 1905, con motivo del centenario del QuijoteHay un ejemplar encuadernado con: El Quijote en las escuelas (Cervantina ...
Casino Republicano Radical (Valencia)   +1 more
core  

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine   +17 more
wiley   +1 more source

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