Results 81 to 90 of about 4,184,658 (417)

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

On radical and torsion theory in the category of S-acts [PDF]

open access: yesarXiv, 2018
In abelian categories like the category of R-modules and even in the category S-Act 0 of S-acts with a unique zero, idempotent radicals and torsion theories are equivalent, and the {\tau}-torsion and {\tau}- torsion free classes of a torsion theory {\tau} are closed under coproducts. These are not necessarily true in the category S-Act of S-acts.
arxiv  

Chinese Character Recognition with Radical-Structured Stroke Trees [PDF]

open access: yesarXiv, 2022
The flourishing blossom of deep learning has witnessed the rapid development of Chinese character recognition. However, it remains a great challenge that the characters for testing may have different distributions from those of the training dataset. Existing methods based on a single-level representation (character-level, radical-level, or stroke-level)
arxiv  

A Manifesto for Radical Children’s Literature (and an Argument Against Radical Aesthetics)

open access: yesBarnboken: Tidskrift för Barnlitteraturforskning, 2019
In The Avant-Garde and American Postmodernity: Small Incisive Shocks (2002), I took for granted that an avant-garde for children was both possible and critically viable.
Philip Nel
doaj   +1 more source

Traditional as radical [PDF]

open access: yes, 2011
An essay that considers the traditional methodologies of making as a model for contemporary sustainable ...
Cox, Sebastian
core  

Quantum Zeno Effect Explains Magnetic-Sensitive Radical-Ion-Pair Reactions

open access: yes, 2009
Chemical reactions involving radical-ion pairs are ubiquitous in biology, since not only are they at the basis of the photosynthetic reaction chain, but are also assumed to underlie the biochemical magnetic compass used by avian species for navigation ...
C. Cohen-Tannoudji   +4 more
core   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

Radical Pasts, Radical Futures

open access: yes, 2022
The final decades of the nineteenth century were marked by unprecedented levels of labor unrest, agitation, and organization in the United States, a period most often remembered, if at all, by way of the Great Railroad Strike of 1877 and the Homestead Steel Strike of 1892, both of which were ultimately broken by the mobilization of state, federal, or ...
openaire   +2 more sources

Organic–Inorganic Hybrid Ladder-like Polysilsesquioxanes as Compatibilized Nanofiller for Nanocomposite Materials

open access: yesMolecules
Nanocomposite materials composed of an organic matrix and an inorganic nanofiller have been the subject of intense research in recent years. Indeed, the synergy between these two phases confers improved properties thanks to an increased surface–volume ...
Dominique Mouysset   +5 more
doaj   +1 more source

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