Results 91 to 100 of about 1,147,538 (315)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

El radical : semanario republicano afecto al Partido Radical: Año I Número 8 - 14 mayo 1932

open access: yes, 1932
Copia digital. Madrid : Ministerio de Cultura.
Partido Radical (Gerona)
core  

From Structure to Vulnerability: Mitochondrial Supercomplexes in Cancer Cells

open access: yesCells
Mitochondrial respiratory supercomplexes are emerging as key regulators of bioenergetics, redox homeostasis, and metabolic plasticity in cancer. Their assembly enhances electron transport efficiency, limits reactive oxygen species production, and ...
Corinne E. Griguer   +2 more
doaj   +1 more source

A Manifesto for Radical Children’s Literature (and an Argument Against Radical Aesthetics)

open access: yesBarnboken: Tidskrift för Barnlitteraturforskning, 2019
In The Avant-Garde and American Postmodernity: Small Incisive Shocks (2002), I took for granted that an avant-garde for children was both possible and critically viable.
Philip Nel
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

El radical : semanario republicano afecto al Partido Radical: Año I Número 7 - 7 mayo 1932

open access: yes, 1932
Copia digital. Madrid : Ministerio de Cultura.
Partido Radical (Gerona)
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

El radical : semanario republicano afecto al Partido Radical: Año I Número 15 - 2 julio 1932

open access: yes, 1932
Copia digital. Madrid : Ministerio de Cultura.
Partido Radical (Gerona)
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

El radical : semanario republicano afecto al Partido Radical: Año I Número 1 - 26 marzo 1932

open access: yes, 1932
Copia digital. Madrid : Ministerio de Cultura.
Partido Radical (Gerona)
core  

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