Results 191 to 200 of about 11,588 (242)

Accessing Molecular Complexity from Methane and Other Gaseous Alkanes via Photocatalytic Cascade Cyclization. [PDF]

Angew Chem Int Ed Engl
Nair AM, Malga JM, Martínez-Acevedo N, Fañanás-Mastral M.   +3 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Photochemical cyclization of α-amino esters to access 3-azetidinones. [PDF]

Chem Sci
Hwang MU, Gogoi A, Scurria M, Gutierrez O, Scheidt KA.   +4 more
europepmc   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Zirconocene(III) in Organic Synthesis: Does the Ugly Duckling Become a Swan? [PDF]

Int J Mol Sci
Rosales J, Chahboun R, Justicia J.
europepmc   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Densely-functionalized bicyclic cyclopentanones by combined photoinduced 6-<i>endo-trig</i> Giese additions and mild aldol cyclizations. [PDF]

Org Chem Front
Viñas-Lóbez J, Sellet N, Fabri B, Levitre G, de Aguirre A, Poblador-Bahamonde AI, Besnard C, Lacour J.   +7 more
europepmc   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Radical docking-migration: a powerful strategy for difunctionalization of alkenes and alkynes. [PDF]

Chem Sci
Cao Z, Chen F, Zhu C.
europepmc   +1 more source

Controllable copper-catalysed photo-induced carbonylative cyclization to access dihydroquinolinones and oxindoles. [PDF]

Chem Sci
Zhao YH, Wang LC, Wu XF.
europepmc   +1 more source