Results 211 to 220 of about 36,700 (277)

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Cu-Catalyzed [1,3]-Fluorine Rearrangement Reactions of <i>N</i>-Fluoroanilines. [PDF]

Org Lett
Nakamura I, Kim J, Suzuki M, Sato T, Terada M.   +4 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

From [NHC─H]^• to Persistent σ-Complex Radicals: Photoinduced Radical Chemistry of Imidazolium Salts. [PDF]

Angew Chem Int Ed Engl
Kolomeychuk FM, van der Zee LJC, Mathew S, de Bruin B, Slootweg JC.   +4 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Mechanistic Design in Photocatalysis. [PDF]

Acc Chem Res
Hardegger R, Wenger OS.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Deciphering Asymmetric Induction in Photoredox Catalysis by Chiral Counteranions. [PDF]

ACS Catal
Baldinelli L, Lerda S, Kayal R, Neese F, De Angelis F, Bistoni G.   +5 more
europepmc   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Site-Selective B─H Activation via HAT Toward Xanthyl-closo-Carboranes as Bench-Stable Precursors of Organosulfur Boron Clusters. [PDF]

Angew Chem Int Ed Engl
Rusconi M, Magi E, Renzi P, Azzi E, Lagostina V, Salvadori E, Chiesa M, Hischa B, Ghigo G, Deagostino A.   +9 more
europepmc   +1 more source